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Xue Yao-ming, Xu Ai-huaDepartment of Endocrinology, Nan Fang Hospital,The FirstMilitary Medical University of PLA, Guangzhou 510515  
In 10 patients with IDDM (5 with retinopathy,5 without retinopathy) and 6 healthy controls the platelet ultrastructurechanges were studied with morphometric method. The results showed that the mean diameter,mean volume,and mean surface areaand the number of the granules and dense bodies of platelet in patients with IDDM increased remarkably.These findings occurredbefore the appearance of diabetic retinopathy and became more evident in patients with retinopathy. These may indicate thatplatelets from patients with IDDM are larger in volume and are in an activated state with more cell organs and platelets play themain role in the initiation and development of diabetic retinopathy.
【CateGory Index】: R587.1
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