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《Chinese Journal of Organ Transplantation》 2006-04
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Immunoadsorption preventing hyperacute rejection of highly sensitized recipients of renal allografts

SUI Wei-guo, YAN Qiang, DONG Li, et al. Medical Department of Renal Transplantation, 181st Central Hospital, Guilin 541002, China  
Objective To investigate immunoadsorption in the prevention of hyperacute rejection in highly sensitized recipients of renal allografts.Methods Immunoadsorption treatment was performed on 10 patients whose panel reactive antigen (PRA) was more than 40 %. The adverse effect and hyperacute rejection were observed.Results Two cases of acute rejection of renal allografts were found in highly sensitized recipients and reversed by the therapy of immunoadsorption and adjusting immuno-suppressive drugs.Conclusion Immunoadsorption treatment could effectively and safely prevent highly sensitized recipients from hyperacute rejection post-transplantation.
【CateGory Index】: R699.2
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