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《Chinese Journal of Organ Transplantation》 2006-04
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Immunoadsorption preventing hyperacute rejection of highly sensitized recipients of renal allografts

SUI Wei-guo, YAN Qiang, DONG Li, et al. Medical Department of Renal Transplantation, 181st Central Hospital, Guilin 541002, China  
Objective To investigate immunoadsorption in the prevention of hyperacute rejection in highly sensitized recipients of renal allografts.Methods Immunoadsorption treatment was performed on 10 patients whose panel reactive antigen (PRA) was more than 40 %. The adverse effect and hyperacute rejection were observed.Results Two cases of acute rejection of renal allografts were found in highly sensitized recipients and reversed by the therapy of immunoadsorption and adjusting immuno-suppressive drugs.Conclusion Immunoadsorption treatment could effectively and safely prevent highly sensitized recipients from hyperacute rejection post-transplantation.
【CateGory Index】: R699.2
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【References】
Chinese Journal Full-text Database 1 Hits
1 Xing Li,Cai Wen-li,Miao Shu-zhai,Qu Qing-shan,Wang Pei-yu,Wang Kai Department of Organ Transplantation,the People's Hospital of Zhengzhou,Zhengzhou 450003,Henan Province,China;Pretreatment of interleukin-2 receptor monoclonal antibody combined with immunoadsorption in 24 sensitized renal allograft recipients[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2009-18
【Co-references】
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1 XIAO Li,SHI Bingyi,WANG Zhen,QIAN Yeyong,CHANG Jingyuan,BAI Hongwei,HAN Mengxia The organ transplant center of P.L.A.,Second Affiliated Hospital of PLA General Hospital,Beijing 100091;Short-term anti-CD25 monoclonal antibody treatment and neogenetic CD4~+CD25~(high) regulatory T cells in kidney transplant[J];Beijing Biomedical Engineering;2008-02
2 WANG Shu-long,ZHANG Gen-fu,HUANG Chi-bing(1.Department of Urology,Hubei Provincial Corps of Chinese People′s Armed Police Forces,Wuhan 430061,China;2.Department of Kidney Transplantation,Xinqiao Hospital,Third Military Medical University,Chongqing 400037,China);Evaluation of the effect of PRA matching in sensitized recipients of renal transplantation[J];Chongqing Medicine;2006-16
3 CHEN Hao,NIE Hai-bo,HU Wei-lie,ZHU Yun-song,ZHAO Yong-bin,ZHANG Xiao-ming,XIAO Yuan-song(Department of Urology,Guangzhou General Hospital,Guangzhou Military Command Area,Guangzhou 510010,China);Peri-operative protein A immunoadsorption in sensitized renal transplant recipients:a case report and literature review[J];Acta Academiae Medicinae Militaris Tertiae;2006-13
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