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Inhibitory Effects of Achene of Great Burdock on Expression of Epstein-Barr Virus Antigens

Chen Tiehong; Huang Di(Guangdong Province Hygiene and Epidemic Prevention Station, Guangzhou 510300)(Cancer Institute, Sun Yat-sen University of Medical Sciences,Guangzhou 510060)  
Ethanol extract of Achene of Great Burdock(AGB)inhibited markedly the expression of EBV-DNase、EBV-DP、EA and VCA in B95-8 cells induced by croton oil and sodium n-butyrate.Inhibitory effects were similar comparing with retinoic acid,a known potent anti-EBV agent, at the same concentration.The experiment also showed that AGB exerted aprolonged inhibitory effect on expression of EBV-DNase and VCA in B95-8 cells which were pretreated with AGB for 7 days and would not restore to the same level as the untreated control group until 12th day after removing the drug.
【CateGory Index】: R285.5
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