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《Chinese Journal of Neurosurgery》 2005-11
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Study on risk factor of severe cerebral vasospasm following aneurysmal subarachnoid hemorrhage

CHEN Gao,ZHANG Jian-min,LI Min,et al.Department of Neurosurgery,The Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310009,China  
Objective To explore the risk factors about severe cerebral vasospasm following aneurysmal subarachnoid hemorrhage.Methods 118 patients with aneurysmal SAH were retrospectively reviewed with clinical and radiological data.The risk factors were analysed statistically.Results The mean age of patients with severe vasospasm was(44.0±10.9) years old.It was obviously younger than the mean age of patients without cerebral vasospasm(52.1±11.4) years old and also younger than that of patients with light or moderate vasospasm respectively(50.7±10.7) years old(P 0.01).In patients with vasospasm,the mean volume of intracerebral hematoma was(24.87±3.72)ml and the mean count of WBC was((17.40±4.1)×10~9/L).The mean volume of intracerebral hematoma and the mean count of WBC in patients with severe vasospasm were larger than those in patients with lightly or moderate vasospasm((18±3.26) ml,)(12.14±2.91)×10~9(P 0.001)and patients without cerebral vasospasm((9±1.41)ml),((9.08±2.16)×10~9)(P 0.001).There was negative correlation between the patient′s age and severity of cerebral vasospasm(r=-0.241,P=0.008).However the volume of intracerebral hematoma and count of WBC are positively correlated with severity of cerebral vasospasm(r=0.694,P=0.001).Conclusions Younger patients,more volume of intracerebral hematoma and larger count of WBC were factors related to the severity of cerebral vasospasm.
【CateGory Index】: R743.35
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