Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Nephrology》 2000-03
Add to Favorite Get Latest Update

Effects of tetrandrine, tetramethylpyrazine and amygdalin on human kidney fibroblast

QU Suilin, FANG Qin, CHEN Gaoxiang, et al. Division of Nephrology, Department of Internal Medicine, First Affiliated Hospital, West China University of Medical Sciences, Chengdu 610041, China  
Objective To study the effects of tetrandrine, tetramethylpyrazine and amygdalin on activity of collagenase secreted by human kidney fibroblasts (KFB ), proliferation, apoptosis and expression of type Ⅰ collagen of human KFB. Methods Activity of type Ⅰ collagenase secreted by KFB, apoptosis, proliferation and collagen Ⅰ expression of KFB were detected by ELISA, flow cytometer, MTT and immunohistochemical method respectively. Results Tetrandrine, tetramethylpyrazine and amygdalin in their respectively optimal concentration range and effective time range enhanced the activity of collagenase secreated by KFB, inhibited proliferation and expression of type Ⅰ collagen of KFB and promoted KFB apoptosis. Conclusion Tetrandrine, tetramethylpyrazine and amygdalin may play important roles in prevention and reversion of renal interstitial fibrosis.
【CateGory Index】: R692.6
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 XU Yan,ZHAI Li hui,ZHU Yue hua \ (Department of Nephrology, The Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, China)\;;THE EFFECT OF ALCOHOL EXTRACT OF CHINESE MEDICINAL HERBS ON HEMODIALYSIS[J];Acta Acadimae Medicinae Qingdao;2003-02
2 LUO Xu,LIN Cai,QIU Ze-liang(Department of Burn.the First Affiliated Hospital of WenZhou Medlcal College,WenZhou,325000,China);Influence of Modified Wuhuang Oil on The Proliferation of Fibroblasts in Vitro[J];Chongqing Medicine;2007-21
3 WEI Lian-bo 1 , MA Zhi-gang 1 , YE Ren-gao 2 , CHEN Bao-tian 1 , ZHAN Sheng-cai 1 , HUANG Huang 11 Department of Traditional Chinese Medicine, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China;Progress of intervention of renal interstitial fibrosis with Chinese traditional herbal medicine[J];Journal of First Military Medical University;2002-10
4 XIU Chun-ying1, CAI Hui2, ZHAO Zhi-ming2, et al (1. Fujian Academy of TCM and Pharmacy, Fuzhou, Fujian 350003, China; 2. Nanjing General Hospital of Nanjing Military Command, Nanjing, Jiangsu 210002, China);Effects of Tetramethylpyrazine on Proliferation and Collagen Synthesis of Cardiac Fibroblast[J];Journal of Fujian University of Traditional Chinese Medicine;2008-02
5 PENG Fang-yi1,JIANG Hai-rong1,CHEN Yuan-xiang1,CHEN Sheng-zhen1,PENG Fang-liang2,ZHAO Wei-bing2,WANG Kai-lin1,WANG Lei1,TAN Hua-ming1,XU Juan1(1.School of Chemistry and Bioengineering,Chongqing University of Technology,Chongqing 400050,China;2.Chongqing Forth People's Hospital,Chongqing 400050,China);Research Progress in Extractive Composition of Eriobotrya Japonica Lind[J];Journal of Chongqing Institute of Technology(Natural Science);2009-09
6 CHEN Zhao-qing,LI Yu,LI Ya-dong(Beijing University of Chinese Medicine,School of Basic Medicine,Beijing 100029,China);Advancement of renal fibrosis treated with TCM from perspective of cytology[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-03
7 YANG Jing hua, ZHOU Qiao ling, CHENG Xiao miao, et al. (Department of Nephrology, Xiangya Hospital, Central South University, Changsha 410008,China);Effects of sodium ferulate on plasma levels of endothelin-1 and nitric oxide in patients with renal hypertension and chronic renal insufficiency[J];Bulletin of Hunan Medical University;2002-05
8 ;Efficacy of Shenanchongji for treating chronic renal failure[J];Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology;2002-02
9 Yang Hongtao,Cao Shili,Huang Congli(the First Affliated Hospital of Tianjin University of TCM,Tianjin,300193);Influence of Shensu Heji on Renal Interstitial Fibrosis of Rats Caused by Adenine[J];Henan Traditional Chinese Medicine;2007-10
10 Qu Suilin *, Wang Zhihui, Fang Qin, Chen Gaoxiang. * Deparment of Nephrology, The First Affiliated Hospital,WCUMS, Chengdu 610041, China;Effects of AngiotensinⅡ on Proliferation and Expression of Interleukin 6 of Human Kidney Fibroblasts[J];Journal of West China University of Medical Sciences;2001-03
【Citations】
Chinese Journal Full-text Database 6 Hits
1 Xu Lieming; Liu Ping; Liu Cheng; Hong Jiahe; Lu Gang; Xue Huiming; Zhu Jianliang and Hu Yiyang(Liver Diseases Research Center,Shanghai Academy of Traditional Chinese Medicien 200032);Observation on the Action of Extractum Semen Persicae on Anti-fibrosis of Liver[J];CHINA JOURNAL OF CHINESE MATERIA MEDICA;1994-08
2 Liu Dewu,Li Guohui,Cao Yong,Su Ziyi,Wang Wen and Wu Xieqing (Burn Institute,The First Affiliated Hospital of Jiangxi Medical College,Nanchang 330006);Observation on Inhibitory Effect of Tetrandrine on Growth of Human Skin Fibroblast in Vitro[J];CHINA JOURNAL OF CHINESE MATERIA MEDICA;1998-01
3 Fan Lie-Ying,Kong Xian-tao,Gao Chun-fang.Department of Clinical Laboraties, Changzheng Hospital,the Second Military Medical University;EFFECTS 0F TETRANDINE ON DNA AND C0LLAGEN SYNTHESIS OF RAT IT0 CELLS AND HEPATOCYTES[J];CHINESE JOURNAL OF DIGESTION;1994-05
4 Zheng Guoqiang, Ye Rengao , Cheng Yongxinng, et al. Institute of Kidney, Sun Yat-sen University of Medical Sciences, Guangzhou 510089;Comparison of growth and apoptosis of fibroblasts derived from kidneys with and without interstitial fibnwis[J];Chinese Journal of Nephrology;1997-02
5 Sun Lin; Yi Zhu-wen; Yu Pei-lan (Dopt of Pediatrics, Second Affiliated Hospital, Human Medical University, Changsha 410011);Effect of Tetramethylhyrazine on Proliferation of Human Fetal Mesangial Cells[J];CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;1995-03
6 Tang Li-long;Wang Li-hui;Zhang Jun-hua;et al(First Affiliated Hospital.Beijing Medical University Beijing(100034);Effect of Tetramethylpyrazine on Expression of Collagen Genes in Primary Cultured Smooth Muscle Cells in Rats[J];CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;1995-11
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 ZHAO Yu-ying et al (The College of Horticulture and Garden, Yangtze University, Jingzhou, Hubei 434025);Research Progress of Amygdalin[J];Journal of Anhui Agricultural Sciences;2005-06
2 ZHAO Yu-ying et al(The College of Horticulture and Garden,Yangtze University,Jingzhou,Hubei 434025);Studies on the Annual Variation of Amygdalin Content in Branches of Apricot[J];Journal of Anhui Agricultural Sciences;2006-01
3 LUO Fu-ying(The Institute Center of Natural Science and Applied Technology,Zhanjiang Normal University,Guangzhou,524048);The Study on Economic Characteristics for the New Plants Reactive Agent Applied to Loquat[J];Northern Horticulture;2007-02
4 Wang Jun, Chen Xiaoxia,Wang Shenqi, et al The Second Hospital Affiliated to Zhejiang College of TCM, Hangzhou(310007);Experimental Research of the Effect of Centella Asiatica Compound on Renal Cytokines mRNA Expression in Mice FGS Model[J];Journal of Zhejiang College of Tcm;2003-06
5 Ma Lijuan, Yang Ruchun, Lu Ying Zhejiang Chinese Medical University, Hangzhou(310053);Effect of Compound Centella Asiatica on UUO Rats’ Renal Fibrosis Transdifferentiation of Kidney[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-06
6 Yu Dongrong Guangxing Hospital Affiliated to Zhejiang University of TCM,Hangzhou (310007);Research on the Mechanism of Intervening Renal Interstitial Fibrosis by Chinese Herbal Medicine[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-06
7 Zhang Xiaoru,Peng Jianwen,Yang Mingzheng,et al People Hospital of Lishui City,Zhejiang Province(323000);Effect of Ligustrazine on Serum TGF-β_1 of Early Diabetic Nephrosis (DN) Patients[J];Journal of Zhejiang University of Traditional Chinese Medicine;2007-04
8 Wang Jie, Lu Yin Jiaxing City TCM Hospital, Zhejiang Province(314001);Research Review on Renal Tubulointerstitial Injury and TCM Prevention and Treatment[J];Journal of Zhejiang University of Traditional Chinese Medicine;2008-06
9 CHEN Su-xian,LI Cai,MIAO Chun-sheng,SUN Bo,TIAN Lin(Department of Pathology,Institute of Frontier Medical Sciences,Jilin University,Changchun 130021,China);Alterations of urotensin Ⅱ contents in blood and urine in Caulis Aristolochiae Manshuriensis-induced renal lesions in rats[J];Journal of Jilin University(Medicine Edition);2007-01
10 WEI Lian-bo 1 , MA Zhi-gang 1 , YE Ren-gao 2 , CHEN Bao-tian 1 , ZHAN Sheng-cai 1 , HUANG Huang 11 Department of Traditional Chinese Medicine, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China;Progress of intervention of renal interstitial fibrosis with Chinese traditional herbal medicine[J];Journal of First Military Medical University;2002-10
China Proceedings of conference Full-text Database 4 Hits
1 Yah Yong-gang Pei Jin Wan De-guang (College of pharmacy ChengDu Traditional Chinese Medicine University,Chengdu 610075,China);Study on the GC-MS Analysis of Fat-soluble Constituents of Semen persicae[A];[C];2007
2 DONG Xinggang,AN Zengmei,DENG Yueyi ; et al (Department of Nephrology,Shanghai Second People Hospital; Shanghai 200011, China);Clinical study of 20 cases patients with IgA nephropathy treated with Chinese herb decoction[A];[C];2006
3 Zhu pijiang,Zhou xun,Zhao hua,et al.Kidney Disease Institute of Integrated Traditional Chinese and Western Medicine of Zhenjiang,Zhenjiang 212028 China;Curative Effect Observation of Qinglijieduhuoxietang Combined With Western Medicine Treatment 45 Example of Refractory Nephrotic Syndrome[A];[C];2009
4 Zhu rong-hui~(1,2),Zhao jun-ning~(1*),Bi yue-qi~1,Wu Yi~(1,2),Yang Xia~(1,2) (1.Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041,China; 2.Chengdu university of TCM,Chengdu 610075,China);Advances in intestinal absorption kinetics of traditional Chinese medicine[A];[C];2009
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 Yi Zhuwen ;Shun Ling (Department of Pediatriecs , Second AffilitedHospital, Hunan Medical University,Changsha );The production and expression of IL-6 infetal mesangial cell (MC)[J];CHINESE JOURNAL OF NEPHROLOGY, DIALYSIS & TRANSPLANTATION;1994-05
2 YS Huang;JT Zhang Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050;ANTIOXIDATIVE EFFECT OF THREE WATER-SOLUBLE COMPONENTS ISOLATED FROM SALVIA MILTIORRHIZ A IN VITRO[J];Acta Pharmaceutica Sinica;1992-02
3 Fan Lie-Ying,Kong Xian-tao,Gao Chun-fang.Department of Clinical Laboraties, Changzheng Hospital,the Second Military Medical University;EFFECTS 0F TETRANDINE ON DNA AND C0LLAGEN SYNTHESIS OF RAT IT0 CELLS AND HEPATOCYTES[J];CHINESE JOURNAL OF DIGESTION;1994-05
4 Xu Lieming , Xie Huaming, Liu Ping, et alShanghai Academy of Traditional ChineseMedicine and Pharmacy ,Shanghai (200032);Change of Fatstoring Cell in Experimental Hepatic Fibrosis and Effect of Extract from Semen Persical on it[J];Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases;1993-02
5 Fan Guang-hui;Xiao Chuang-qing;Chen Ju-mei;et al(The 163th Hospital of PLA,Changsha 410003);Effect of Ligustrazine on Plasma Lipid Peroxidation,Superoxide Dismutase of the Coronary Heart Disease[J];CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;1994-01
6 唐利龙,汪丽惠,朱国英,张均华;Effect of Wu Lin Powder and Its Ingredients on Atrial Natriuretic Factor Level in Mice[J];CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;1995-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved