Percutaneous radiofrequency ablation of liver malignancies
ZHANG Zhijian, WU Mengchao, CHEN Han, et al. Eastern Hepato biliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China
Objective To describe the safety and efficacy of percutaneous radiofrequency ablation (PRFA) to treat liver canc er. Methods One hundred patients with histolog ically or clinically confirmed primary or metastatic malignancies were treated p ercutaneously under ultrasound guidance using LeVeen multipolar array needle ele ctrode and RF 2000 generator between October, 1999 and October, 2000. All patie nts were followed up to assess complication, treatment response, recurrence and curative effect. Results PRFA was performed in 76 patients with primary liver cancer and 24 patients with metastatic liver can cer. AFP positive of small hepatic cancer (inoperative) became AFP negative in 7 50% patient (21/28). The rate of completely concreted necrosis of small hep atic malignancies shown by MRI was 859%(61/71). Conclusion s PRFA as a local thermal therapy is a kind of new palliative t reatment for hepatic malignancies. It is minimally invasive, safe and effecti ve especially for small hepatic tumers and can also be used in conjunction with TACE for larger ones.
【CateGory Index】： R735.7