Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Laboratory Medicine》 2006-10
Add to Favorite Get Latest Update

Current status of resistance and its prospects of β lactamases in China

CHEN Min-jun. Department of Clinical Laborotory,Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China  
The aim of this paper is to try to decrease the rate of bacterial resistance to β-lactams, to recover partially its activity, then strengthen clinical efficiency of those antibiotics. Firstly we introduced surveillance results of SEANIR Program in China in which 15 hospitals from 14 cities of 13 provinces participated. There was big difference in rate of resistance of clinic strains to antibiotics between 15 hospitals. Three main reasons for the difference were analyzed. Secondly the great success in study on relationship between consumption of antibiotics and resistance rate of special organisms in Europe was introduced. AND We strongly recommend that similar study should be started in China for educating clinic personnel and helping administration officer to make guideline of hospital infection control.Lastly, we introduced the mathematical models of epidemiology and population genetic of antibiotics treatment.We also conclude that resistance in communities and in hospital can be controllde by reducing the rate of consumption of antibiotics, by reducing the by overall rate of transmission of resistance-strains, by correctly using antibiotics, by increasing the rate at which patients leave the hospital and by preventing entering patient with resistance-pathogens from mixing with other patients before those bacteria cleared.
【CateGory Index】: R515
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 9 Hits
1 XU Xiaofeng,XU Chenhuai.Hangzhou sanatorium of nanjing molitary rejion hangzhou 310007,China;Spectra and drug resistance of pathogenic bacteria in 520 septicemia patients from Jan. 2006 to Dec. 2007[J];Journal of Clinical Internal Medicine;2008-08
2 ZHANG Jian-fang, FAN Xin, SU Ming-quan,WANG Jing, LIU Jia-yun,CHENG Xiao-dong,YUE Qiao-hong, XU Xiu-li, SUN Yi-qun, HAO Xiao-ke(Center of Clinical Laboratory, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, Shaanxi Province,China);Prevalence of Ambler Class A and D β-lactamase and Drug Susceptibility of Pseudomonas aeruginosa[J];Parasitoses and Infectious Diseases;2008-02
3 ZHU Jin-mei(Faculty of Laboratory Medicine,Chongqing Zhongshan Hospital,Chongqing 400013,China);A comparative study of distribution and drug resistance of extended-spectrum beta-lactamases-producing pathogens between a tertiary care hospital and a second grade care hospital[J];Journal of Shanxi Medical University;2008-05
4 XIE Xiao-jun,WU Shao-yuan,WANG Chong,ZENG Zhong-ming(Xili People's Hospital,Shenzhen,Guangdong 518055,China);Incidence of Metallo-beta-lactamase-producing Pseudomonas aeruginosa and their Antibiotic Resistance[J];Chinese Journal of Nosocomiology;2009-14
5 LI Ming(Central Blood Bank of Jining Red Cross,Jining 272011,Shandong,China);Analysis on the drug resistance of Escherichia coli to drugs containing enzyme inhibitor[J];Journal of Pathogen Biology;2007-04
6 YU Lian-hua,MOU Si-hua,HU Da-kang,RUAN Xiao-Yu(Taizhou Municipal Hospital,Taizhou 318000,China);Study on drug-resistance of community-acquired Staphylococcus aureus in children[J];Chinese Journal of Health Laboratory Technology;2009-04
7 LIU Jian-ming1, NIE Xin-min2, SUN Shen-hua1, LIU Bei-zhan1(1.Department of Respiratory Diseases, 2.Department of Laboratory Test, the Third Xiangya Hospital of Central South University,Changsha, Hunan 410013, P.R.China);Detection and resistance research of producing AmpC β-lactamases or ESBLs in Enterobacter cloacae[J];China Journal of Modern Medicine;2008-21
8 GAO Guo-xiang,LIU Fei(General Hospital of Jihua Group Company,Jilin,Jilin 132021,China);Major Pathogenic Bacteria of Prostate Infection and Drug Resistance Analysis[J];Chinese Journal of Nosocomiology;2010-05
9 LI Ming,WU Runzhuan(Department of Laboratory,Dongguan Taiping People's Hospital,Guangdong Province,Dongguan 523900,China);The uropoiesis infects disease germ's drug resistance monitor[J];China Modern Medicine;2010-31
Chinese Journal Full-text Database 10 Hits
1 LIAO Wei-jiao,JIANG Jie-hua,YI Jian-yun,XU Yun-jian,PAN Si-zeng.Department of Clinical Laboratory,The First Affiliated Hospital of Guangzhou Medical College,Guangzhou 510120,China;The appearance of a novel CMY type class C cephalosporinase (AmpC) in southern China[J];Journal of Chinese Physician;2006-05
2 ZHAO Jing-kun1, WANG De-sheng1, DUAN Shu-rong1, WANG Jian-xiu1, BAI Jing2, LI Wen-lan2 1Department of Neurology, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China; 2Institute of Pharmaceutical Research, Harbin University of Commerce, Harbin 150086, China;Fingerprinting of Fuzhisan by high-performance liquid chromatography with ultraviolet and evaporative light scattering detector[J];Journal of Southern Medical University;2007-12
3 LU Yan,WU Guo-juan(Department of Animal Science and Technology,Beijing Agricultural College,Beijing,102206,China);Progress on the Detection Methods of Penicillin in Livestock Products[J];Progress in Veterinary Medicine;2006-07
4 ZHANG Li,ZHANG Hui-jie,WANG Ping,et al.(Department of Pharmacy,the Second Affiliated Hospital,Nanjing Medical University,Nanjing 210011,China);Analysis of Antibiotic Application among Inpatients during 2008[J];Journal of Hubei University for Nationalities(Medical Edition);2009-02
5 Lin Jie Huang Xiaorong Zhang Jia Zheng Jing Tang Minying Chen Bin (Fujian Entry - Exit Inspection & Quarantine Bureau, 350002; College of Animal Science,Fujian Agriculture and Forestry University,350003);Rapid Detection Of Penicillin Residues in Chicken by Radioimmunoassay Method[J];Fujian Journal of Animal Husbandry and Veterinary;2006-03
6 Bo Haibo *1,2 , Liu Chunhui 1, Zhang Hongli 1, Li Yongmin 1, Chen Liren 1 1(Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000) 2(Qinghai Entry-Exit Inspection and Quarantine Bureau, Xining 810000);Direct Injection Determination of Oxytetracycline, Tetracycline andChlortetracycline in Honey by the High Performance LiquidChromatography with Column Switching Technique[J];Chinese Journal of Analytical Chemistry;2005-04
7 Lu Xiaoling~1,Ni Kunyi~(1),Tu Jie~2,Jia Huning~1,Yu Qingfeng~1,Wang Lei~2~1(Department of Analysis Chemistry,China Pharmaceutical University,Nanjing 210009)~2(Shenzhen Pharmaceutical Factory,Shenzhen 518029);Analysis of the Antibiotics of β-Lactam by Micellar Electrokinetic Capillary Chromatography[J];Chinese Journal of Analytical Chemistry;2006-02
8 FAN Ying-ying1,QI Lu2 and YANG Shu-min3(1.CITIC GUOAN MENGGULI Powder Source Technology Co.LTD,Beijing 102200;2.PeKing University,Bejing 100871;3.Doping Control Center of China,Bejing 100029);Determination of 5 penicillin residues in pork by HPLC/MS/MS(trap)[J];Chinese Journal of Analysis Laboratory;2007-12
9 ZHANG Yong-Long1, LI Jia-Tai1, ZHAO Ming-Wu21(Institute of Clinical Pharmacology, the First Hospital,Beijing Medical University,Beijing,100083) 2(The Third Hospital,Beijing Medical University,Beijing,100083);DEVELOPMENT IN AMP C ENZYME[J];THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY;1999-05
10 WU Wei-Yuan, CHEN Min-Jun, WANG Hui (Department of Clinical Laboratories, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730);The Detection of Derepressed AmpC Enzyme and Extended-Spectrum β-Lactamases in Enterobacter Cloacae[J];The Chinese Journal of Clinical Pharmacology;2001-02
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 ZHONG Bai-yun,ZHANG Yun-li,ZHU Lin,LI Xian,LIU Wen-en(Xiangya Hospital,Central South University,Changsha 410008,China);Detection of AmpC gene and investigation of drug resistance in Enterobacter cloacae[J];Chinese Journal of Infection Control;2009-04
2 Chen Zhao-li~(1,2),Wang Ting~2,Li Chang-qing~2,Zhang Xing-yan~(1,2),Cheng Ze-neng~1 (1 Department of Pharmaceutical Analysis,College of Pharmacy,Central South University,Changsha,410013; 2 Xiangbei Welman Pharmaceutical Co.Ltd,Changsha,410000 );Development in Studies of Inhibition of Tazobactam Against β-lactamaes[J];World Notes on Antibiotics;2010-04
3 ZHANG Yun-li,ZHU Lin,LIU Wen-en.(Department of Clinical Laboratory,Xiangya Hospital,Central South University,Changsha 410008,China);Prevalence of plasmid-mediated AmpC beta-lactamases in the Klebsiella pneumoniae strains isolated in Changsha[J];Chinese Journal of Infection and Chemotherapy;2009-06
4 WANG Qun 1,YANG Yong-hong 2,GENG Wen-jing 2,WU De-jing 2,YUAN Lin 2,YU Sang-jie 2,SHEN Xu-zhuang 2 (1.Department of Pediatrics,the Affiliated Hospital of Guilin Medical College,Guilin 541001,Guangxi Zhuang Autonomous Region,China;2.Laboratory of Microbiology and Immunology,Beijing Children′s Hospital Affiliated to Capital Medical University,Beijing 100045,China);Clinical Characteristics and Antibiotic Resistance of Staphylococcus Aureus from Skin and Soft Tissue Infections in Children[J];Journal of Applied Clinical Pediatrics;2009-22
5 LI Ming,WU Runzhuan(Department of Laboratory,Dongguan Taiping People's Hospital,Guangdong Province,Dongguan 523900,China);The uropoiesis infects disease germ's drug resistance monitor[J];China Modern Medicine;2010-31
6 YAN Wen-qiang,XIE Ming-shui,HUANG Hong-yao(Central Hospital of Suizhou,Suizhou,Hubei 441300,China);Drug Resistance of Pathogenic Bacteria Causing Chronic Bacterial Prostatitis in Senile Patients[J];Chinese Journal of Nosocomiology;2010-24
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved