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《National Medical Journal of China》 2002-03
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Idiopathic retroperitoneal fibrosis: a clinical analysis of 7 cases

JIANG Ming, ZHANG Sizheng, PAN Weidong, ZENG Xuejun, ZHANG Pisheng. Department of Rheumatology, Peking Union Medical College Hospital, Beijing 100730, China  
Objective To investigate the clinical characteristics of idiopathic retroperitoneal fibrosis. Methods The clinical manifestations, laboratory examination, and CT and MIR features of seven patients with idiopathic retroperitoneal fibrosis were analyzed. Results (1) The initial symptoms were nonspecific and variable and included abdominal pain, low back pain, and weigh loss. Later symptoms, depending on the organs affected, included abdominal mass, ascites, urinary symptoms, and and intestinal obstruction. (2) Diagnosis of IRF could be based on elevated erythrocyte sedimentatio rate and gamma globulin and positive findings by CT and MIR. For masses in retroperitoneal space and adhesion of abdominal organs, CT was more sensitive than B mode untrasonography. However, for hydronephrosis and lesions in ureter, B mode ultrasonography was the first choice. (3) Steroid and immunosupressant were effective during the early stage of IRF. In the advanced stage, operation was necessary. Conclusion Imaging examination is important for diagnosis of IRF. However, the final diagnosis depends on patjological examination. Treatment depends on the stage of disease. The prognosis is optimistic.
【CateGory Index】: R572.2
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