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《Chinese Journal of Nosocomiology》 2007-02
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Distribution and Resistance to Antibiotics of Shigella in Anhui Province

HU Li-fen*,CHENG Jun,LI Jia-bin,WANG Zhong-xin,LI Xu (*The First Affiliated Hospital,Anhui Medical University, Hefei,Anhui 230022,China)  
OBJECTIVE To investigate the distribution and the resistance rate of Shigella in Anhui Province to guide the choice of antibacterials. METHODS Ninety one strains of Shigella were cultured in Sep 2005.The groups were identified by biochemical and serologic tests.Susceptibility of 91 strains of Shigella in Anhui to various antibiotics was tested using standardized custom dilution MIC panels according to CLSI(2005) guidelines. RESULTS There were 57 strains of Shigella flexneri,31 strains of S.sonnei and 2 strains ofS.boydii among 91 strains of Shigella.The resistance rates of Shigella to cefoperazone/sulbactam and piperacillin/tazobactam were remarkably lower than to other third generation cephalosporins.The susceptible rates to carbopenems were 100%.The resistance rates to ciprofloxacin lactate and pazufloxacin mesilate were 27.47% and 32.97%,respectively. CONCLUSIONS There is a certain resistance rate of the Shigella to fluoroquinolones and the third generation cephalosporins.More attention should be paid to the surveillance and control of such resistance.
【Fund】: 国家自然科学基金项目(30571654)
【CateGory Index】: R446.5
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