Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Nosocomiology》 2010-06
Add to Favorite Get Latest Update

Antibacterial Use Density in a Hospital

DU De-cai,ZHOU Shu-ming,SHEN Ai-zong,JIANG Ling(Provincial Hospital Affiliated to Anhui Medical University,Hefei 230001,China)  
OBJECTIVE To provide an evidence for rational use of antibacterials in the clinic through analysis of the antibacterial use in a hospital.METHODS By retrospective study,the data of drug used from 2004 to 2008 were collected and analyzed by Excel 2003.Taking defined daily dose(DDD) as the unit,antibacterial use density(AUD) was calculated and carried on the analysis.RESULTS The AUD was fluctuant during the last 5 years.The third generation cephalosporins,penicillin/beta-lactamase inhibitors and the second generation cephalosporins ranked in the first three places in turn.The drug ranking in the first ten places came from cephalosporins,penicillin/beta-lactamase inhibitors,nitromidazoles,and fluoroquinolones and the majority of antibacterials were injection.Comparing with the domestic and foreign hospital,AUD in the hospital was significantly lower than the average level of China's.The use of antibacterials was different from South Korea and America.CONCLUSIONS The hospital may exist such problems as overmedication,dense medication and the high use ratio of broad-spectrum antimicrobial agents.Cephalosporins,penicillin/beta-lactamase inhibitors and fluoroquinolones should be strictly limited in the clinic to avoid an excessive increase in AUD.
【CateGory Index】: R96
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 9 Hits
1 LIANG Chen-fang//The No.4 Affiliated Hospital of Guangxi Medical University,Liuzhou 545005,China;Medication and drug-resistance of the third generation cephalosporins[J];Acta Medicinae Sinica;2005-02
2 MENG Li-hui,ZHENG Jia,LI Ting(Beijing Tongren Hospital,Capital University of Medical Science,Beijing 100730,China);Quantified evaluation and analysis of antimicrobial usage[J];Chinese Journal of Infection Control;2006-04
3 FENG Xia,ZHANG Chunmei,ZHONG Yi(Dept.of Pharmacy,The Second Affiliated Hospital of Guangzhou Medical College,Guangzhou 510260);Analysis of the Use of Antibacterials in a Teaching Hospital During the Period 2000~2004[J];Evaluation and Analysis of Drug-use in Hospital of China;2005-06
4 PENG Yongfu,XIA Peiyuan,LIU Songqing(Dept.of Pharmacy,Southwest Hospital,Third Military Medical University,Chongqing400038,China);Analysis of Consumption of Antibiotic/Beta-Lactamase Inhibitor Preparations in18Hospitals of Chongqing During the2001~2003Period[J];China Pharmacy;2005-01
5 REN Nan, WU An-hua, FENG Li, WEN Xi-mao, YI Xia-yun, L Yi-xin, GONG Rui-e; HUANG Xun, WANG Man-ping (Xiangya Hosptal, Central South University, Changsha, Hunan 410008, China);Clinical Application of Antimicrobial Agents for Inpatients: A Cross Section Investigation[J];Chinese Journal of Nosocomiology;2006-09
6 XIAO Yong-hong,WANG Jin,ZHAO Cai-yun,GAO Lei,ZHENG Bo,XUE Feng,LI Xiang-yan,HAO Feng-lan,On behalf of Mohnarin(Institute of Clinical Pharmacology,The First Hospital,Peking University,Beijing 100083,China);Mohnarin Bacterial Resistance Surveillance 2006-2007[J];Chinese Journal of Nosocomiology;2008-08
7 AN Li-qing,LIU Zhuo-la,DUAN Jin-ju,LIU Jian-guo,ZHANG Su-ping,LIU Li-hua,LIU Jian-li,ZHANG Liu-ping(Jinzhong First People's Hospital,Jinzhong,Shanxi 030600,China);Changing Patterns of Nosocomial Infection Pathogens and Drug-resistance 2001-2005[J];Chinese Journal of Nosocomiology;2009-04
8 Yang Xin-yun 1,Hong Zheng 2,Wu Yu-xin 1 and Wang Yu-sheng 3 (1 The First Affiliated Hospital of Guangzhou Medical College,Guangzhou 510120;2 West China School of Pharmacy,Sichuan University,Chengdu 610041;3 West China Medical Center,Sichuan University,Chengdu 610041);Characterization of β-lactamase inhibitors reduced susceptibility in clinical isolates of Escherichia coli and Klebsiella pneumoniae[J];Chinese Journal of Antibiotics;2004-06
9 Zhang Lihua, Shang Qian, Yu Qingping(The Third Affiliated Hospital of InnerMongolia Medical College, Baotou 014010,P. R. China);Correlation Between Amount of Consumption of Third - generation Cephalosporins and Drug Resistance of Escherichia coli and Klebsiella pneumoniae[J];China Pharmacist;2006-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WANG Shuai-bing,XIONG Liang-wei,CHEN Xiao-lan(Jiangsu Animal Husbandry & Veterinary College,Taizhou,Jiangsu,225300,China);Mechanism and Countermeasure of Antibacterial Drug Resistance in Animal Husbandry and Breeding[J];Progress in Veterinary Medicine;2009-06
2 HUANG Rui-juan1,2,YE Lin-xiang1,FENG Qi-ming3(1.Tongji Medical College of Huazhong University of Science and Technology,Wuhan 430030,China;2.Nanxishan Hospital of Guangxi Zhuang Autonomous Region,Guilin 541002,China;3.Guangxi Medical University,Nanning 530021,China);A case-control study on risk factors for extended-spectrum β-lactamases produced by Escherichia coli[J];Chinese Journal of Infection Control;2007-04
3 QIN Ya-qin,YAN Hong-xia,LIU Zhi-an,ZHAO Wen(Dongguan Tungwah Hospital,Zhongshan University,Dongguan 523100,China);Evaluation on management achievement in preventive antimicrobial application in surgical operations[J];Chinese Journal of Infection Control;2008-03
4 ZHU Zhen-xiang1,TAO Qiong2,CAO Yan3,LI Jia-bin4(1.Department of Infections Diseases,The First Affiliated Hospital of Anhui Medical University,Hefei Anhui 230022;2.Department of Clinical Laboratories,Lu′an People′s Hospital,Lu′an Anhui 237005;3.Department of Clinical Laboratories,Traditional Chinese Hospital of Lu′an,Lu′an Anhui 237005;4.Anhui Center for Surveillance of Bacterial Resistance,Hefei Anhui 230022,China);Bacterial resistance surveillance in Lu′an city in 2008[J];Journal of Bengbu Medical College;2009-08
5 XIAO Yong-hong(Peking University First Hospital,Beijing 100191,China);Antimicrobial resistance surveillance and management for rational use of antimicrobial agents[J];Chinese Journal of Infection Control;2009-04
6 Ding Fan,Huang Xiaoming,Wang He. Department of Microbiology,Guiyang Medical College,Guiyang 550004,Guizhou,China;Primary study on trend analysis of Ceftazidime-resistance of E.coli by Linear fitting[J];Guizhou Medical Journal;2009-10
7 WANG Qian,SUN Feng-jun,XIA Pei-yuan(Department of Pharmacy,Southwest Hospital,Third Military Medical University,Chongqing 400038,China);Relationship of macrolide-resistant phenotypes with biofilm formation and icaA-genetypes of clinically isolated Staphylococcus epidermidis[J];Acta Academiae Medicinae Militaris Tertiae;2009-22
8 HU Long-Hua,XIONG Jian-Qiu,YU Xiao-Jun,YU Cheng-Lin,JIA Kun-Ru,HU Xiao-Yan.Second Affiliated Hospital of Nanchang University,Nanchang 330006,China;Comparison of the antimicrobial resistance of Staphylococcus aureus isolated from children and adults in vitro[J];Chinese Journal of Contemporary Pediatrics;2009-12
9 WANG Ailing1 FU Mingxia2 SONG Xiangqin1 AN Xinye1 ZHAO Hongmei11 Department of Inspection,Affiliated Hospital of Binzhou Medical University,Binzhou 256603;2 Binzhou People's Hospital;Evaluation of four techniques for detection of meticillin-resistant Staphylococcus aureus[J];Journal of Binzhou Medical University;2009-06
10 WU Lei1a,CAI Shao-xi1a,GENG Sui-na1b,LIU Lai-yu1a,TONG Wan-cheng1a,LIU Gang1a(1.a.Department of Respiratory Diseases;b.Clinical Laboratory,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China);Analysis on the prognosis factor of nosocomial pneumonia due to Pseudomonas aeruginosa in Southern Hospital during 2006-2009[J];The Chinese Journal of Clinical Pharmacology;2010-03
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Lin Qingan,Lai Guoxiang,Huang Lianghu;Drug Sensitivity on Extended-spectrum β-lactamases Producing Clinical Strains in FuZhou[J];Fujian Meidical Journal;2002-02
2 ZHANG Yong-Long LI Jia-Tai (Institute of Clinical Pharmacology, Peking University First Hospital, Beijing 100083);The in vitro Activity of Sulbactam in Combination with Third Generation Cephalosporins Against Third Generation Cephalosporins Resistant Bacteria[J];THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY;2000-05
3 YI Xia-yun, GUO Si-jiang, LI Xian, ZHANG Jin-xiang, LI Jie (Xiangya Hospital, Central South University, Changsha 410008, China);Comparison of resistance of the common Gram-negative bacilli to the third cephalosporins[J];Chinese Journal of Infection Control;2004-01
4 Yu Yong, Sheng Zhiyong, Chai Jiake et al. Burns Institute, 304 Division, General Hospital of PLA, Beijing 100037, China;Relationship between antibiotic related factors and changes in constituent ratios of main pathogens in burn infection[J];Medical Journal of Chinese People's Liberation Army;2006-01
5 WANG Hui *, ZHU Jian xin, LIU Yong, et al ( *Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China);Resistance pattern of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in four chinese hospitals from 1999 to 2000[J];Chinese Journal of Infection and Chemotherapy;2001-03
6 Li Dongmei et al. (Dept. Clinical Lab., Shantou Central Hospital, Shantou 515031)\;;RESISTANCE SURVEILLANCE TO FOURTEEN ANTIBIOTICS AND MIC OF MAIN GRAM-NEGATIVE BACILLI[J];JOURNAL OF MICROBIOLOGY;2000-03
7 LI Jianglin,XU Quanying(The Dept. of Pharmacy,The People's Hospital of Shenzhen,Shenzhen 518020);Analysis of the Amount of Consumption of Third-generation Cephalosporins and Situation of Drug Resistance in Our Hospital During 1998~2001 Period[J];Evaluation and Analysis of Drug-use in Hospital of China;2002-04
8 CHEN Yongchuan,LIU Songqing,WANG Zhangyang(Southwestern Hospital,Third Military Medical University,Chongqing 400038);Evaluation of Clinical Therapeutic Effect of Amoxicillin/sulbactam in Treating Bacterial Infections[J];China Pharmacy;2001-07
9 CHEN Minling,ZHANG Shunguo(Dept of Pharmacy,Xinhua Hospital,Shanghai Second Medical University,Shanghai 200092)HUANG Kun(Institute of Scientific and Technical Information,Shanghai Drug Supervision and Administration Bureau,Shanghai 200040);Analysis of Antibiotics Used in 47 Hospitals of Shanghai During the Period 2000~2002[J];China Pharmacy;2003-11
10 PENG Yongfu,XIA Peiyuan,LIU Songqing(Dept.of Pharmacy,Southwest Hospital,Third Military Medical University,Chongqing400038,China);Analysis of Consumption of Antibiotic/Beta-Lactamase Inhibitor Preparations in18Hospitals of Chongqing During the2001~2003Period[J];China Pharmacy;2005-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved