Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Primary Medicine and Pharmacy》 2006-12
Add to Favorite Get Latest Update

Clinical investigation on the immune state of patients with hepatic cirrhosis and primary hepatic carcinoma

JIANG Jing.Department of Gastroenterology,The Second Affiliated Hospital of Dalian Medical University,Dalian,Liaoning 116027,China  
Objective To study the immune state and correlated strategy of patients with hepatic cirrhosis and primary hepatic carcinoma.Methods 17 patients with hepatic cirrhosis and 8 patients with primary hepatic carcinoma(PHC) in our hospital were collected since 2002.The indexcs of immune function were detected in all patients and some were re-examined.Results It was found that although the immune index varied in patients suffering from severe liver diseases,some regularities were shown as follows:(1)CD4 and CD4/CD8 in T lymphocyte subset declined markedly(P0.05) and CD8 was suppressed.(2)The number of T lymphocyte subset and NK cell decreased in cirrhotic patients,cirrhotic patients with hepatic encephalopathy and patients with PHC.The most significant descendent tendency was shown in patients with PHC compared with cirrhotic patients.(3)The number of T lymphocyte subset showed positive relation with that of NK cells and negative relation with humoral immune reaction(plasma globulin).Conclusion The treatment of PHC with interleukin-2 has shown that the level of CD4 could be suitable index on drug efficiency and interleukin-2 therapy can adjust severe disorder of immune system.
【CateGory Index】: R575.2;R735.7
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 3 Hits
1 CHEN Zhao-xiu1,XU Jian-min2,WANG Xiao-cui1,LI Ai-guo1,TIAN Xiang-ping2,YANG Huan-dong3 The Wei Fang Yi Du Center Hospital,1Blood Transfusion Department,2Gestroenterology,3General Surgery Department(Shandong Qingzhou,262500);Changes and significance of immune function in hepatitis patients with liver cirrhosis and ascites before and after fresh frozen plasma transfusion[J];Chinese Journal of Current Advances in General Surgery;2011-11
2 ZHOU Huajian ZENG Hong Department of Gasteroenterology,Huizhou Central Hospital,Guangdong 516001;Effect of Intestinal Flora and Cellular Immune Function in Patients with Posthepatitic Cirrhosis[J];China Modern Doctor;2009-08
3 ZHOU Jian-hua Department of Laboratory,Dongguan Changping Hospital,Dongguan,Guangdong 523573,China;Study on serum variation of liver cirrhosis patients with spontaneous peritonitis and cytokines in ascites[J];Chinese Journal of Primary Medicine and Pharmacy;2007-08
【Citations】
Chinese Journal Full-text Database 5 Hits
1 Zhao Caiyan,Liu Jinxing,Zhen Zhen,et al.Third Hospital of Hebei Medical University,Shijiazhuang 050051;Changes and correlation of serum IL-2、sIL-2R、IL-6、T subsets in patients with liver cirrhosis and hepatocellular carcinoma[J];CHINESE JOURNAL OF PRACTICAL INTERNAL MEDICINE;1999-01
2 Yao Shukun Li Sheng-mian Li Zhihui et al(Fourth Affiliated Hospital,Hebei Medical University Shijiazhuang 050011);Assessment of T Cell Subset and Natural Killer Cell Activity in Liver Cirrhosis and Primary Hepatic Carcinoma[J];CHINESE JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY;1997-03
3 WANG Chao 1,GAO Zhi\|hong 1,JIA Hong_ling 2 (1.The First Affiliated Hospital,Dalian Medical University,Dalian 116011,China;2.Hongqi Hospital of Mudan Jiang Medical College,Mudan Jiang 157000,China);MEASUREMENT AND IMPLICATION SERUM IMMUNOGLOBULINS AND PERIPHERALTLYMPHOCYTE SUBSETS IN PATIENTS WITH HEPATIC DISORDERS[J];Journal of Postgraduates of Medicine;2002-08
4 CAO Zhi-xin,CHENG Xiao-ping,WU Zai-de(Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology ,Wuhan 430030,China);Study on T lymphocyte subsets immunological condition of spleen in hepatocellular carcinoma with liver cirrhosis[J];Chinese Journal of General Surgery;2002-06
5 WANG Min, WANG Fusheng, LIU Jingchao. Division of Biological Engineering,Institute of Infections Diseases, The 302 Hospital of PLA, Beijing, 100039;Association of peripheral blood lymphocyte subsets with disease progression in patients with chronic hepatitis B infection[J];Chinese Hepatology;2003-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 GAO Yong,HUANG Chen,TAN Yi,LIU Jin-xin,LI Zong-kuang,LIU Hui-chun,CUI Pei-yuan(Department of General Surgery,Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China);Changes of spleen function of hepatic cirrhosis after liver transplantation in rats[J];Journal of Bengbu Medical College;2007-02
2 LIU Hong.Department of infection,the People's Hospital of Linyi,Shandong(276003),China;Study of CD28 expressions and CTL,Ts in chronic hepatitis B patients[J];International Journal of Digestive Diseases;2008-06
3 Zhang Facan,Chen Jiexiong(Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021);ASSESSMENT OF RED BLOOD CELL IMMUNITY AND T LYMPHOCYTE SUBSETS IN HEPATOPATH[J];Journal of Guangxi Medical University;1999-06
4 DU Er-qiu1,ZHENG Jiu-sheng2(1.2006 Grade of Medical Department of Graduate School,Nanchang University;2.Department of Obstetrics,the Women and Children HealthHospital of Jiangxi,Nanchang 330006,China);The Characteristics of T Lymphocyte Subsets in Cord Blood in Neonates after Intrauterine Infection with Hepatitis B Virus[J];Acta Academiae Medicinae Jiangxi;2009-02
5 DENG Chun-cheng, LIU Xiao-guang, LIU Bo, et al. ( Hematology Laboratory of Zhoushan Hospital, Zhoushan 316004, China);Clinical significance of measurement of CD_(19)~+CD_(25)~+ cells in peripheral blood from patients with hepatic cirrhosis.[J];Chinese Journal of Clinical Hepatology;2006-05
6 Niu Ming hua, Zou Xiao ping, Gao Feng, et al Department of Gastroenterology, Ankang Railroad Hospital, Xi an 725000;The Characteristics of Intestinal Flora in Patients with Liver Cirrhosis and its Therapeutic Observation[J];Chinese Journal of Clinical Gastroenterology;2002-03
7 KAN Xiao1,SUI Yun2,HAN Shao-lei1,CAO Chuang-jie1,ZHENG Zhao-min1(1.Jinan Infectious Disease Hospital,JiNan 250021;2.The Second People's Hospital of Jinan,Jinan 250021);The effect of PGE-interferon-alpha2a on peripheral T lymphocyte subsets in Patients with chronic hepatitis B[J];Basic & Clinical Medicine;2011-10
8 NI Yong-liang,LI Qing(Department of Urology,Qianfoshan Hospital of Shandong University,Jinan 250014,China);Clinical effectiveness of dendritic cells therapy combined with intravesical perfusion of epirubicin on bladder cancer after TURBT[J];Journal of Shandong University(Health Sciences);2011-02
9 ZHANG Ya(Fujian College of TCM,Fuzhou,350003,China);Correlation between the Syndrome Type and T-lymphocyte Subgroups and NK Cells in the Peripheral Blood of Chronic Hepatitis B[J];Shanxi Journal of Traditional Chinese Medicine;2005-05
10 LUO Zu-jun,LI Yan-hua(The People's Hospital of Heng-gang,Shenzhen,Guangdong 518115,China);Analysis and clinical significance of expression of apoptotic related proteins on peripheral blood Th cell in chronic hepatitis B patients[J];Journal of Practical Medical Techniques;2008-04
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 QIANG Ren,XU Jian-ru.Department of Infectious Disease,The Third People's Hospital,Nanton City,Nanton 226001,China$$$$;Relationship Between Transforming Growth Factor β 1 and Tumor Necrosis Factor α with Liver Fibrosis in Chronic Viral Hepatitis Subjects[J];Journal of Chinese Physician;2001-07
2 LU Wei 1 , LI Yan-hao 1 , HE Xiao-feng 1 , CHEN Yong 1 , ZENG Qing-le 1 , QIU Yu-rong 2 Departments of Interventional Radiology 1 and Clinical Laboratory 2, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China;Effect of dosage of anticancer agents during transcatheter arterial chemoembolization on T cell subsets in patients with hepatocellular carcinoma[J];Journal of First Military Medical University;2002-06
3 WU Zhong-wen, LI Lan-juan. Department of Infectious Disease, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou310003,China;Cirrhotic complications and intestinal microflora[J];International Journal of Epidemiology and Infectious Disease;2006-01
4 ZHI Hui,LUO Bao-ming~*,WEN Yan-ling,YANG Hai-yun,OU Bing,MA Jian-hong(Department of Ultrasound in Medicine,the Second Affiliated Hospital of Sun Yat-Sen University,Guangzhou 510120,China);Comparative study on treatment of small hepatocellular carcinoma by radiofrequency ablation and percutaneous ethanol injection[J];Chinese Journal of Interventional Imaging and Therapy;2006-04
5 ZHENG Mu-bai,WANG Jun-ling,LI Xiu-ying,PAN Quan,CAO Ai-mei(Dezhou Peoples Hospital in Shandong Province,Dezhou 253014,China);Study of regional cell immune response on ultrasound guided superantigen injection with anhydrous ethanol injection therapy for hepatocellular carcinoma[J];Chinese Journal of Interventional Imaging and Therapy;2007-03
6 KONG Li, YAO Shu -kun, ZHANG Rui -xing, et al. (Department of Liver Diseases, the Third Hospital of Hebei Medical University, He Bei, Shijiazhuang, 050051 , China );The levels of TGFβ1, IL-12, IFNγand other cytokines in patients with primary hepatic carcinoma and their clinical significances[J];Chinese Journal of Clinical Hepatology;2006-04
7 ZHANG Guo-shun,SHANG Hua,MA Li-zhuan,et al.Digestion Department of Affiliated Hospital of North China Coal Medical College,Tangshan 063000,China;Clinical Study of PEG-IFN alpha-2a with Thymosin α1 in Treatment of Chronic Hepatitis B[J];Chinese General Practice;2010-25
8 LI Cai-xia LI Chuan-fu CAO Chi (Dept.of Radiology,Qilu Hospital of Shandong University);Influence on patients' cellular immunity in hepatocellular carcinoma by TACE[J];Acta Academiae Medicinae Shandong;2003-05
9 ZOU Xiao-mei, WANG Jian-cheng, XIA Hong-bo, et al. Department of Ultrasound ,The Second People's Hospital of Jingzhou, Hubei Province, Jingzhou 434000, China.;The application of ultrasound-guided percutaneous ethanolInjection therapy for post-operative recurrence of liver cancer.[J];Journal of Modern Oncology;2006-03
10 WANG Dong-wen,MA Qing-jiu,DU Xi-lin,et al. Department of General Surgery,Tangdu Hospital,Forth Military Medical University,Xi'an,710038;Changes of Soluble Interleukin-2 Receptor and T lymphocytes Subsets in Patients with PHC After Rodiofrequency Ablation[J];The Practical Journal of Cancer;2001-04
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 LIU Xuhua1,HE Weifeng2,WENG Weijun3 (1.Department of Gastroenterology,Huicheng District Chinese Medicine Hospital,Huizhou City,Guangdong Province,Huizhou 516001,China;2.Department of Hepatology,Huizhou Municipal Central Hospital,Huizhou 516001,China;3.Department of Operating Room,the Third People's Hospital of Huizhou City,Huizhou 516001,China);Study on microecologics in the treatment of Spontaneous Bacterial Peritonitis[J];China Medical Herald;2010-23
【Secondary Citations】
Chinese Journal Full-text Database 4 Hits
1 LI Yu-zhong,HU Hong,WANG Min (Departiment of clinical Laboratory,the Second Affiliated Hospital, Dalian Medical University,Dalian 116027,China);The Changes of T-lymphocyte subsets and Nature killer Cell Quantity in Patients with hepatic diseases[J];Journal of Dalian Medical University;2001-01
2 CAO Zhixin,CHEN Xiaoping,WU Zaide.Hepatic Surgery Center,Ton gji Hospital,Tongji Medical College,Huazhong University of Science and Technol ogy,Wuhan 430030,China;A study on the spleen Th1/Th2 cytokines immunological condition in the patients with primary hepatocellular carcinoma combined with liver cirrhosis[J];Chinese Journal of Experimental Surgery;2001-06
3 CAO Zhixin, CHEN Xiaoping, WU Zaide Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030, China;Changes of immune function in liver cirrhosis patients after splenectomy combined with resection of hepatocellular carcinoma[J];Chiese Journal of Surgery;2002-02
4 Pan Jicun,Xu Xin,Jiang Sen et al.Department of Gynecology,Affiliated Hospital,Shandong Medical University,Jinan 250012;CLINICAL SIGNIFICANCE OF THE DETERMINATIONS OF INTERLEUKIN 6 IN SERUM AND ASCITES OF THE PATIENTS WITH OVARIAN CANCER[J];CHINESE JOURNAL OF IMMUNOLOGY;1997-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved