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《Chinese Journal of Critical Care Medicine》 2004-02
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Study on the form changes of peripheral blood cells and its related factors in the primary hypertension

NIE Ying-juan,MENG Qing-yi,ZHOU Bao-lin, et al. Emergency Department,Chinese PLA General Hospital,Beijing 100853,China  
Objective To investigate the form changes of peripheral blood cells in the primary hypertension.Methods The blood cell form and serum chemical analysis data in 160 cases with primary hypertension(HP group)and 1 751 medical workers with normal blood pressure (control group)were collected and analyzed.Results The white blood cell count,red blood cell count,hemoglobin, hematocrit,mean cell hemoglobin concentration, red cell distribution width and platelet distribution width in the HP group were higher than those in the control group (all P0.05); and the mean platelet volume in the HP group was lower than that in the control group.Both systolic blood pressure(SBP)and diastolic blood pressure (DBP)levels correlated highly with the age,body weight,serum triglyceride,serum creatine and monocyte cell percentage(r=0.071~0.398,all P0.05).The SBP level also correlated well with the blood sugar,white blood cell count,hemoglobin,red cell distribution width and platelet distribution width(r=0.092~0.222,all P0.01).The serum GPT level,triglyceride,blood sugar and creatine in HP group were also higher than those in the control group,and the serum total cholesterol and blood urea nitrogen had no significant difference between two groups(all P0.05).Conclusion The changes of peripheral blood cell form are present in the patients with primary hypertension.That may be related to the onset of acute and chronic complications in the hypertension progress.
【Fund】: 解放军总医院院长基金项目 ( 2 0 0 2 -1)
【CateGory Index】: R544.1
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