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《Chinese Journal of Critical Care Medicine》 2004-06
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Clinical study of traumatic cerebral edema by treatment with β-sodium aescinate

ZHANG Li-yuan, CHEN Jing, ZHAO Zhu-qing, et al. Department of Emergency,the Affiliated Hospital of the Medical School of Jiangsu University,Zhenjiang 212001,China  
Objective To compare the curative effects of β-sodium aescinate and mannitol on the treatment of traumatic cerebral edema.Methods 152 cases of traumatic cerebral edema confirmed by CT were divided into two groups randomly,one group was treated with β-sodium aescinate(administration group),the other with mannitol(control group). In the administration group,40~60 mg β-sodium aescinate dissolved in 500 mL G.S(5%) were given by intravenous drip.In the control group,only 250 mL mannitol (20%) were given 2~4 times per day,then 20~40 mg dexamethasone were given by intravenous injection (IV).Results The effectiveness ration in the administration group was 100%,but 72.09% in the control group.Noticeable differences were observed( P 0 01).Conclusion β-sodium aescinate is an ideal medicine for the treatment of traumatic cerebral edema.
【CateGory Index】: R651.1
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