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STUDIES ON SAGAMICIN PRODUCED BY M.ECHINOSPORA MUTANT STRAIN II. SELECTION AND FERMENTATION OF M.ECHINOSPORA JIM-401

Zhao Min, Fan Jin and Bo Jian-xin (Jiangsu Institute of Microbiology, Wuxi)  
Micromonospora echinospora, a gentami-cin producing strain, after successive muta-genic treatments by UV and Lithium chloride, a mutant strain NO. 29-26 was obtained. Conducting further the mutant by natural selection, we obtained another mutant strain, designated as JIM-401. M. echinospora JIM-401 produced Saga-micin and Gentamicin C_1a as its main components. This paper deals with the preliminary investigation on the strain selection and fermentation studies.
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