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Studies on specific metabolites of Streptomyces avermitilis E107

Wang Xiao wei, He Jian yong and Bai Xiu feng (Shenyang Parmaceutical University, Shenyang 110015)  
Two metabolites termed as E107a and E107b were isolated from the mycelium of Streptomyces avermitilis E107 by means of solvent extraction, thin layer chromatography and HPLC. Based on phsico chemical properties and data of EI MS, HRFAB MS, UV, IR, 1 H NMR, 13 C NMR and DEPT, the major component E107a was identified as Oligomycin A and the possible structure of E107b was proposed.
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