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Effects of Gynostemma Pentaphyllum on Cognitive Functions of Cerebral Infarct Patients

Yan Jiongjiong, Yue Wenhao, Han Danchun et al, Shandong Medical University, Jinan  
Objective: To investigate the effects of Gynostemma Pentaphyllum(GP) on cognitivefunctions of cerebral infarct (CI) patients. Method:A total of 76 cases were studied, including 32 randomly selected CI patients on GP (Group A), 21 CI patients on Piracetam (Group B), and 23 matched normal elderly controls on GP (Group C). All subjects received drugs for a period of 12 weeks, and they were assessed before and after drug administration on several cognitive scales, including the Clinical Memory Scale (CMS), the Wechsler Memory Scale (WMS), and the HRB-RC. Results:(1) After the 12-week drug period, Group A obtained compatible MQ scores to Group C, while both groups showing better improvement than Group B. (2) After taking GP, Group A showed better improvement in cognitive functions than Group C, especially on the Category Test. The administration of GP improved cognitive functions of CI patients to a level close to that of normal elderly subjects.Conclusions:The present results provide support for the favourable effects of GP on improving cognitive functions of CI patients, which have significant clinical implications for the treatment and prevention of cerebral infarct conditions.
【CateGory Index】: R743.31
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