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《Chinese Journal of Gerontology》 2005-04
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Neuron adhesion mechanism in substantia nigra compacta of Parkinson's disease mice by electroacupuncture therapy correlated to dopaminergic neural plasticity

TANG Yong, YU Shu-Guang,CHEN Jin. Lab of Chronobiology, Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, China  
Objective To explore the effect of neural cell adhesion molecule(NCAM)on dopaminergic plasticity of substantia nigra compacta (SNC) in Parkinson's disease (PD) mice enhanced by electroacupuncture (EA). Methods PD model mice induced by 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine were as subjects. Hegu and Taichong were punctured once daily, 7 times as one period. The expressions of NCAM and NCAM mRNA were determined by immunohistochemistry and in situ hybridization after three periods. Results The NCAM(92.67±2.52)and NCAM mRNA(230.33±17.16)positive cells in EA group were higher than those(54.00±10.39, 138.33±5.86)in model group (P0.05, P0.01).Conclusions EA could promote the expression of NCAM and NCAM mRNA in PD mice SNC and enhance degenerative dopaminergic neuron plasticity.
【Fund】: 国家中医药管理局课题资助(国中医药科0203JP41)
【CateGory Index】: R245.5
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Chinese Journal Full-text Database 2 Hits
1 Lu Li Bai Limin~△Sun Hongmei Hong Qingtao (Department of Anatomy,Beijing University of Traditional Chinese Medicine,Beijing 100029,China);Effect of electroacupuncture on microglia activation in vitro[J];Chinese Journal of Anatomy;2007-02
2 TANG Yong, YIN Hai-Yan, ZENG Fang, YU Shu-Guang ( Institute of Biomedical Engineering, West China Center of Medical Science, Sichuan University, Chengdu, Sichuan Province 610041, China; Department of Experimental Acupuncture, Acupuncture & Tuina College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province 610075, China);Pondering in-situ induction of endogenous neural stem cells in hippocampus of rats with Alzheimer disease by acupuncture[J];Journal of Chinese Integrative Medicine;2005-05
China Proceedings of conference Full-text Database 1 Hits
1 WU Qiaofeng LU Shengfeng YU Shuguang (Chengdu university of TCM,Chengdu 610075);The role of silent synapse in synaptic plasticity and neurological rehabilitation improving by Acupuncture[A];[C];2010
Chinese Journal Full-text Database 10 Hits
1 TANG Xiao Jing 1,LI Yu Hua 1,CHEN Wei 2,CHEN Rong 3,CHENG Rui 3,LI Yi Ping 1,2,3** 1. Life Science College, Beijing Normal University, Beijing 100875, China 2. Forsyth Institute, Harvard School of Dental Medicine, Boston, MA 02115, USA 3. Zhejiang Cell Biomedical Research College, Hangzhou 310006, China;Cloning and characterization of a novel mouse gene BSG5 cDNA specifically expressed in early embryo brain[J];Acta Zoologica Sinica;2004-04
2 Yao Yisang 1) Fu Jiaqi 1) Chen Wei 3) Yang Wei 1) Zou Xing 1) Li Ning 4) Li Yiping 1,2,3,4) ( 1)Biomedical Research Institute, 2)Key Laboratory of cell proliferation and regulation Biology of Ministry of Education, College of Life Science,Beijing Normal University; 3)The Forsyth Institute, Harvard University,02115,Boston,USA; 4)Zhejiang Cell Biomedical Research College,310006,Hangzhou,China);CLONING AND CHARACTERIZATION OF A NOVEL MOUSE GENE bsg3 cDNA SPECIFICALLY EXPRESSED IN BRAIN[J];Journal of Beijing Normal University(Natural Science);2004-03
3 WANG Jing,LIU Kaiyan △ (Institute of Hematology,Beijing University People's Hospital,100044,China);Method of differentiation of adult humen bone marrow mesenchymal stem cell into Schwann like cells in vitro[J];Journal of Beijing Medical University;2003-02
4 WANG Chun-hua*, JIN Wei-zhe*, JIANG Xiao-dan. *Department of Histology and Embryology, Basic Medical College, Jiamusi University, Jiamusi 154007, Chin a Corresponding author: JIANG Xiao-dan, Email:jiangxiao_dan@163.com;Structure and action of neural cell adhesion molecules in nervous system[J];Chinese Journal of Neuromedicine;2005-05
5 WANG Chun-hua*, JIN Wei-zhe*, JIANG Xiao-dan, LIU Yue-xia*, XU Ru-xiang, CAI Ying-qian. *Department of Histology and Embryology, Basic Medical College, Jiamusi University, Jiamusi 154007, China;Experimental study on the detection of NCAM receptor and ultrastructure of rat BMSCs-D-NSCs[J];Chinese Journal of Neuromedicine;2005-09
6 ZHAO Ze wen,CHANG Qing,LIANG Zhi qing,et al. (Department of Obstetrics and Gynecology,Southwest Hospital,the Third Military Medical University,Chongqing 400038,China);Study on the effects of polychlorinated biphenyl congener PCB_(153) on embryonic development by using in vitro post-implantation mouse whole embryo culture[J];Chongqing Medical Journal;2004-05
7 PENG Xi jia,LIU Shao zhang,YE Jian (Department of Ophthalmology, Daping Hospital,Third Military Medical University,Chongqing 400042,China);Oligodendrocyte and regeneration of optic nerve[J];Journal of Traumatic Surgery;2002-03
8 TIE Li Jun, PAN Jian Ping, GE Ling, et al. Department of Pediatrics, First hospital of Medical College, Xi'an Jiaotong University, Xi'an 710061, China.;Effect of Thyroid Hormones on Expression of GAP-43 in Cerebellum of Neonatal Rats[J];Chinese Journal of Contemporary Pediatrics;2001-01
9 WANG Shi jun, FAN Hui min, QIN Wei, YIN Zheng qin (Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Developing changes of electrophysiological properties of visual cortical neurons in rats[J];Acta Academiae Medicinae Militaris Tertiae;2003-08
10 GAO Peng-fen, YIN Zheng-qin, LIU Ying-bing, WANG Shi-jun, HU Zhi-an (Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Effects of age and visual experience on the synaptic function development in rat visual cortex[J];Acta Academiae Medicinae Militaris Tertiae;2003-21
China Proceedings of conference Full-text Database 1 Hits
1 Ayimuguli~1,CAI Yong~2,Wei Suo cheng,Huo Sheng-dong,LI Guo rong~1 (1.Life Science and Engineering College of Northwest Minorities University,Lanzhou 730030: 2.Science Experiment Center of Northwest Minorities University,Lanzhou 730030);The Morphological Development of JingNing Chicken Embryo Brain[A];[C];2010
Chinese Journal Full-text Database 10 Hits
1 XU Zhen-hua,XU Neng-gui,YI Wei,FU Wen-bin,JIN Rui(Deptartment of Acupuncture and Moxibustion,the Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Guangdong Guangzhou 510120,China);The Improvement of Synaptic Plasticity in the Rat Dentate Gyrus after Stroke by Acupuncture[J];Journal of Anhui Traditional Chinese Medical College;2007-03
2 WANG Shou biao\ (Department of Anatomy, Qingdao University Medical College, Qingdao 266021, China)\;;A STUDY OF THE EFFECTS OF EARLY-RECOVERY TRAINING ON EXPRESSIONS OF GAP-43 mRNA AND P38 mRNA IN ISCHEMIC PENUMBRA IN RATS[J];Acta Acadimae Medicinae Qingdao;2003-02
3 XING Guogang, LIU Fengyu, WAN You △, YAO Lei, HAN Jisheng (Neuroscience Research Institute, Peking University; Department of Neurobiology, Peking University School of Basic Medical Sciences, Beijing 100083, China);Electroacupuncture of 2 Hz induces long-term depression of synaptic transmission in the spinal dorsal horn in rats with neuropathic pain[J];Journal of Peking University(Health Sciences);2003-05
4 TIAN Derun 1,2 , LI Xiaodong 1,2 , NIU Dongbin 1, SHI Yushun 1, Jaw Kang CHANG 3, HAN Jisheng 1△ (1.Neuroscience Research Institute, Peking University, Beijing 100083,China;2.Department of Anatomy, Tianjin Medical University; 3. Phoenix Inc, USA);Electroacupuncture up-regulated arcuate nucleus α-MSH expression in the rat of diet-induced obesity[J];Journal of Peking University(Health Sciences);2003-05
5 WANG Yun, WANG Xiaomin, HAN Jisheng(Neuroscience Research Center, Beijing Medical University, Beijing 100083);EFFECTS OF 2 Hz and 100 Hz ELECTROACUPUNCTURE TOLERANCEON THE TRANSCRIPTION OF CNS κ OPIOID RECEPTOR mRNA[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1998-01
6 ZHAO Ji lan, YU Shu guang, ZHOU Qi zhi, et al (赵纪岚,等) Acupuncture, Moxibustion and Tuina College, Chengdu University of TCM (Chengdu, 610075,China);Influence of Acupuncture to the Contents of Neurotransmitter in Central Nervous System of Senile Rats and Mice[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1999-03
7 TANG Yong, YU Shu-guang,CHEN JinAcupuncture & Tuina college, Chengdu University of Traditional Chinese Medicine,(Chengdu,610075,China);Enhanced Synapstic Plasticity in Parkinson's Disease Mice Sunbstantla Nigra by Electroacupuncture Therapy[J];Journal of Chengdu Unversity of Tarditional Chinese Medicine;2005-01
8 ZHANG Li~1,TANG Yong~(2,3),YU Shu-guang~3(1.Clinical Department,Medical College,Tibet University,850000;2.Institute of Biomedical Engineering,West China Center of Medical Science,Sichuan University,610041;(3.Chengdu University of Traditional Chinese Medicine,610075);Incrased Expression of Dopamine Transporter in Parkinson's Disease Mice Substantia Nigra by Electroacupuncture Therapy[J];Journal of Chengdu University of Traditional Chinese Medicine;2006-03
9 Zhu Jie, Yu Shuguang Zhao Jinan, et al Chengdu University of TCM (Chengdu,610075,China);Influence of Blood Rheology of Senile Mice Treated by Acupuncturing Yungch'uan (K 1) Acupoint[J];JOURNAL OF CHENGDU UNVERSITY OF TARDITIONAL CHINESE MEDICINE;1997-02
10 ZHOU Huifang, XUE Bing, LI Yan, NIU Dongbin, WANG Xiaomin Neuroscience Institute, Peking University, Beijing 100083, China;Inflammatory/immune in vitro model of Parkinson' s disease[J];Chinese Journal of Neuromedicine;2003-01
【Secondary References】
Chinese Journal Full-text Database 6 Hits
1 WANG Xiaoyue1,ZHOU Lisha2(1.Postgraduate student of Hubei College of Traditional Chinese Medicine,Wuhan,Hubei,430061;2.Medical College of Jiang Han University,Wuhan,Hubei,430065);Effects of Electroacupuncture on bFGF of AD Model Rat's Hippocampal Neural Stem Sells and Study Memory Ability[J];Journal of Hubei College of Traditional Chinese Medicine;2008-01
2 Chen Lingli,Li Xinhua,Chen Beiyang,Mo Li(Hunan Medical University School of Medicine,Changsha 410007);Tendons acupuncture points Yanglingquan substantia nigra in Parkinson's mouse model of TH expression[J];Guiding Journal of Traditional Chinese Medicine and Pharmacy;2010-11
3 CHENG Hai-yan PENG Ying-mei YU Jian-chun~ΔHAN Jing-xian~Δ(Molecular Biology Laboratory,First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine;Acupuncture and Moxibustion Research Institute of Tianjin,Tianjin300193,China);Research Progress on Brain Cell Proliferation[J];Progress in Modern Biomedicine;2008-02
4 ZHOU Li-sha1,WANG Xiao-yue2(1.School of Medicine Science,Jianghan University,Wuhan 430056,China;2.Hubei College of Traditional Chinese Medicine,Wuhan 430065,China);Effects of Electroacupuncture on AD Model Rat Hippocampus Neural Stem Cells Nestin and Impact on Learning and Memory Capacity[J];Journal of Jianghan University(Natural Sciences);2008-02
5 QIAO Xiu-Lan,LU Sheng-Feng,YIN Hai-Yan,et al.Chongqing Municipal Hospital of Traditional Chinese Medicine,Chongqing 400013,China;Influence of acupuncture and moxibustion on neural stem cell proliferation and differentiation in SAMP8 mice cortex[J];Chinese Journal of Gerontology;2010-01
6 SHEN Mei-hong,TANG Qing-qing,LI Zhong-ren,MA Cheng(The Second College of Clinical Medicine,Nanjing University of Chinese Medicine,Nanjing 210029,China);Effect of Electroacupuncture on Hippocampal LTP in Alzheimer's Disease Rats Induced by Aβ_(25-35)[J];Acupuncture Research;2010-01
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Ma Jun,Tian Qing,Chen Xionghua,et al Hubei College of TCM(430061);Influence of Acupuncture on NOS in Cerebral Cortex of the Rats with Parkinsons Disease[J];JOUNAL OF HUBEI COLLEGE OF TRDITIONAL CHINESE MEDICINE;2000-02
2 Liu Yueting,Sun Zhidong,Li Shoujian.Departemnt of Neurosurgry,The First Hospital of Shanxi Medical University,Taiyuan 030001\;;Contrast study of microelectrode guided post-ventrual pallidotomy and Chinese medicine for treatment in Parkinson disease[J];Chinese Journal of Stereotactic and Functional Neurosurgery;2001-03
3 WANG Ling ling 1, HE Chong 1, LIU Yue guang 1, ZHU Li li 2 ( 1 Second Clinical College of Nanjing University of Traditional Chinese Medicine,Nanjing,Jiangsu,210029,China; 2 Affiliated Hospital of Nanjing University of Traditional Chinese Medici;Effects of Acupuncture on Brain Stem Evoked Potential in Patients with Parkinson's Disease[J];JOURNAL OF NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE;2000-04
4 HUANG Wen-yan Shanghai Institute of Acupuncture and Meridian;Influence of Electric Stimulation of Scalp Acupuncture on Electromyogram in Tremor Pattern of Parkinson's Disease[J];ACTA UNIVERSITATIS TRADITIONIS MEDICALIS SINENSIS PHARMACOLOGIAEQUE SHANGHAI;2000-03
5 XU Bing 1, MA Cheng 1, CHEN Guo zhi 2, 1. Key acupuncture laboratory of Jiangsu province, acupuncture institute of Nanjing TCM university, 210029, China; 2. Nanjing brain hospital, China;The Influence of Acupoint Injection on Central Monoamine Transmitters in Parkinson's Disease[J];Shanghai Journal of Acuuncture and Moxibustion;2002-02
6 MA Jun, TIAN Qing, WANG Yan-chun, WANG Hua Hubei College of Traditional Chinese Medicine, Wuhan 430061, China;Influence of Electro acupuncture on the Content of Glutamine in Striatum of Parkinson's Disease Rats[J];Shanghai Journal of Acupuncture and Moxibustion;2003-01
7 Dong Xiaotong, Wang Shuangkun, Ren Xiaoqun, et al (Institute of Acupuncture and Moxibustion, China Academy of TCM, Beijing, 100700);Effects of Acupuncture Treatment on Blood LPO and SOD Contents in Parkinsonism Patients[J];Acupuncture Research;2001-01
8 Liang Xibin,Liu Xianyu,Li Fengqiao,Zhang Wangming,Wang Xiaomin,Han Jis heng (Neuroscience Research Institute, Peking University, Beijing, 100083;A Mechanism Study on the Effect of Electroacupuncture on A Partially Lesioned Rat Model of Parkinson's Disease[J];Acupuncture Research;2001-03
9 Ma Jun, Wang Hua (Hubei College of TCM, Wuhan, 430061);Effect of Electroacupuncture on TH Content in Mesencephalic Substantia Nigra of PD Rats[J];Acupuncture Research;2001-04
10 Wei Baoqiang,Liaoning Basic Medical Institute,S henyang 110005,Liaoning Province,ChinaBao Aili,Clinical Laboratory,Benxi Municip al Center Hospital ,Liaoning Province,Benxi 117000,ChinaZhang Guangxin 1 ,Niu Lifeng 2 ,Su Dan 2 ,Cui Zenghong 3 ,He Xiaoming 3 ,Wang Yuqin 3 ,Zhang Kun 1 ,1 Depatment of Anatomy,2 Diagnostics and 3 Physiology,Vocational and Technological School,Liaoning College of Tra-ditional Chinese Medicine,Shenyan g 110005,Liaoning Province,China;Ultrastructural changes of substantia nigra,caudate nucleus and raphe nucleus in rat model of parkinsonism[J];Modern Rehabilitation;2003-13
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