Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Coal Industry Medicine》 2004-02
Add to Favorite Get Latest Update

EFFECT OF β-ENDORPHIN LEVEL ON CELLULAR IMMUNOLOGIC FUNCTION OF ASPHYXIA NEWBORNS

Xiao Li,Cai Dingbang,Zhuang Siqi,et al.Department of Pediatrics,The First people's Hospital of Zhaoqing,Guangdong 526021  
Objective To observe the dynamic changes of cellular immunologic function (T-cell subpopulation) and β-endorphin(β-EP) level of asphyxia newborns,and to explore β-EP's regulation mechanism of cellular immune. Methods All cases were divided into two groups: asphyxia group (45 cases) and normal group(20 cases). Two blood samples were collected at the first day and the seventh day after birth,β-EP, were detected. Results Compared with normal group,cellular immunologic function of asphyxia group were inhibited obviously and the degree was positive to asphyxial degree.Level of β-EP increased significantly,(201.45±82.97)pg/ml in normal group,(335.22±75.82)pg/ml in mild asphyxia group,(882.45±112.37)pg/ml in severe asphyxia group(P0.01).There were significant difference in level of β-EP,CD3,CD4,CD8 among groups(P0.05).To asphyxia group,there were significant correlation between level of β-EP and immunologic indexes except CD8,correlation coefficient (r)was 0.457~0.728. Conclusion Cellular immunologic function of asphyxia newborns are inhibited obviously and inhibited degree is positive to asphyxial degree,β-EP play a role in inhibited regulation of the cellular immunologic function.
【CateGory Index】: R722.12
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Lu-fen1,YAN Ming-ru1,CHENG Jin-lian2,et al(1 School of Acupuncture and Moxibustion,Beijing University of Chinese Medicine,Beijing 100029;2 Beijing Hospital of Traditional Chinese Medicine);Effect of acupuncture on β-EP levels of plasma,hypothalamus, pituitary and lymph node in rats with adjuvant-induced arthritis[J];Journal of Beijing University of Traditional Chinese Medicine;2007-01
【Citations】
Chinese Journal Full-text Database 3 Hits
1 BAIHAI BO, DUJI ZENG #, ZHENGXIAO XIANG (Department of Biological Science and Medical Engineering, #Department of Biological Science and Technology, Zhejiang University, Hangzhou 310027);β ENDORPHIN INVOLVED IN THE REGULATION OF HUMORAL IMMUNE FUNCTION OF RATS DURING ACUTE HYPOXIA [J];ACTA PHYSIOLOGICA SINICA;1999-03
2 WANG Xiaolei, LIU Xiaoping, LIU Kai, et al. The Third Municipal Hospital of Chengdu 610031, CHINA;Study On Apoptosis And [Ca~(2+) ]i Infulx In Lymphocytes Of The Neonatal Piglets Following Hypoxia Ischemia[J];CHINESE JOURNAL OF PERINATAL MEDICINE;1999-04
3 LIN Jiayou,LI Li, GAO Yang. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and PUMC, Beijing 100005;Enhancement expression of IL 1_β, IL 6 and iNOS gene in human peripheral blood mononuclear cells by β endorphin[J];CHINESE JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY;1999-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Chinese Traditional Medicine Hospital of Lu'an, Anhui 237006 WANG Yao- you;67 cases of nursing diagnosis and nursing measures of neonatal asphyxia[J];Journal of Anhui Health Vocational & Technical College;2003-06
2 ZHANG Zhen-bin,PAN Yi-guang Lu'an People's Hospital,Lu'an 237005,Anhui;Comprehensive diagnosis of newborn's HIE[J];Journal of Anhui Health Vocational & Technical College;2008-03
3 Xu Jiali, Sun Qi Department of Pediatrics, Affiliated Hospital of Bengbu Medical College, Anhui, Bengbu 233004;257 patients clinical features of neonates with hypoxic-ischemic encephalopathy[J];Anhui Medical Journal;2004-04
4 XU Jia li,KONG Ping,SUN Qi,SHI Hua (Department of Pediatrics,Affiliated Hospital of Bengbu Medical College,Anhui 233004,China);Treatment of neonatal hypoxic ischemic encephalopathy with naloxone[J];Journal of Bengbu Medical College;2004-03
5 LUO Min,LIU Xiao-ling,LI Cui-fang,SU Hong(Department of Pediatric,Anqing First People's Hospital,Anqing 246003,China);Analysis of the clinic manifestation and intracranial CT of 1 28 asphyxia neonatorum[J];Journal of Bengbu Medical College;2005-05
6 HAN Min~ 1,2 ,PAN Jia-hua~1,LI She-hui~2,ZHENG Li-hua~2,YE Xiao-qin~2,WANG Zi-bin~2,YUAN Jian-qiang~2,KONG Xian-zhen~2,GAO Xia~2 (1.Department of Pediatrics;Anhui Provincial Hospital,Affiliated to Anhui Medical University,Hefei 230001 2.Department of Pediatrics,Bengbu Third People’s Hospital,Bengbu 233000,China);Effect of continued treatment on prognosis of newborns with hypoxic ischemic encephalopathy[J];Journal of Bengbu Medical College;2006-06
7 LI Ya Department of Paediatrics, Yueyang Maternal and Child Health Care Hospital, Yueyang 414000, China;Observation of curative effect of neonatal hypoxic-ischemic encephalopathy: retrospective analysis of 186 cases[J];Chinese Journal of Neuromedicine;2004-02
8 XIAO Mei-bao. Department of pediatrics, People's Hospital of Hanshan County, Hanshan 238100, China;Early application of sodium phenobarbital in the prevention of brain injury following asphyxiation in neonates[J];Chinese Journal of Neuromedicine;2005-08
9 LI Hong, FENG Zhi-chun, ZHOU Xi-zhong, FANG Su-zhen, ZHAO Qian. Department of Peadiatrics, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China;The effect of neurotrophic drugs on the infants with hypoxic-ischemic encephalopathy during convalescent period[J];Chinese Journal of Neuromedicine;2005-11
10 ZHUANG Ming-hua~* LUO Jian-ming~* LIU Ming-fa~* BAI Ye.~*Department of Neurosurgery,Second Affiliated Hospital,Medical College,Shantou University,Shantou 515041,China;Acupuncture on Conception Vessel,Governor Vessel and Bladder Channel to increase neural stem cell proliferation in neonatal SD rats after hypoxic-ischemic insult[J];Chinese Journal of Neuromedicine;2006-07
【Co-references】
Chinese Journal Full-text Database 8 Hits
1 WT4”BX]LIU Jing, et al [WT4”HX](Beijing Yanhua Hospital,Beijing 102500,China) [WT5HZ][ST5BZ];The variation of cord blood interleukin-6 and tumor necrosis factor-alpha and nitric oxide in neonatal hypoxic-ischemic encephalopathy and its clinical implication[J];HEBEI MEDICINE;2000-11
2 XU Fa-lin~1,ZHU Chang-lian~1,CHENG Xiu-yong~1,JIA Li-ting~2,GENG Lin-lin ~1,QIAO Jun-ying~1,HU Sheng-hai~3(1.Department of Pediatrics;2.Department of Radioimmunity;3.Department of Pharmacy, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,China);Changes of Cytokines Measurement in Serum and Cerebrospinal Fluid in Asphyxia Ne onates and Its Relationship with Prognostic[J];Journal of Applied Clinical Pediatrics;2005-08
3 Lin Niyang, Fang Xi-aoyi , Wu Beiyan ,et al. The First Affiliated Hospital of Shantou University Medical College,Shantou, 515041;THE CLINICAL SIGNIFICANCE OF T LYMPHOCYTIC SUBGROUP AND BL-6, IL-8 LEVELS IN PERIPHERAL BLOOD OF NEONATAL HIE[J];The Journal of Neonatology;2002-05
4 LIU Jing,SUN Shao-yong,SHEN Lu-sheng. Department of Neonatology,Beijing Obstetrics and Gynecology Hospital,Capital University of Medical Sciences,Beijing 100026,China;Effects of perinatal asphyxia on immune function in umbilical blood of neonates[J];Chinese Journal of General Practitioners;2003-03
5 LIU Jing, MENG Fanhang, RONG Xiaoping. Beijing Yanshan Petrochemical Company Worker's Hospital 102500, China;Immunological Study on Neonatal Hypoxic-ischemic Encephalopathy[J];Chinese Journal of Perinatal Medicine;2002-02
6 HU Dian 1,GU Hang 1,HONG Xin-ru 2,et al. 1 Department of Obstetrics and Gynecology,the Affiliated Changzheng Hospital of the Second Military Medical University,Shanghai 200003,China [;Study on the relationship between endogenous opioid peptides and neonatal asphyxia[J];Chinese Journal of Critical Care Medicine;2003-09
7 Xiao Li *,Cai Dingbang,Zhuang Siqi,et al. *Department of Pediatrics,the First People's Hospital of Zhaoqing,Zhaoqing 526021,China;Research on changes and mechanism of immunologic function in newborns with asphyxia[J];Chinese Journal of Practical Pediatrics;2004-10
8 Li Xiaohong,et al)Beijing University of Traditional Chinese Medicine,Beijing 100029,China;The effect of neurotrophic factor in chronic irritability rats with moxibustion at dazhui point[J];Acta Chinese Medicine and Pharmacology;2002-06
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 LIU Jun-ling,CHEN Shu-ping,GAO Yong-hui,MENG Fan-ying,WANG Jun-ying(Institute of Acu-moxibustion,China Academy of Chinese Medical Sciences,Beijing 100700,China);Observation on the Analgesic Effect of Repeated Electroacupuncture and Its Relation to Changes of Plasma β-EP,ACTH and COR Levels[J];Acupuncture Research;2007-05
【Secondary Citations】
Chinese Journal Full-text Database 7 Hits
1 Liu Jing, Li Hua, Zhao Li, et al Dept. of Pediatrics, Beijing Yanhua Hospitial, Beijing 102500;Study on Immunity Function in Neonatal Asphyxia[J];Chinese Journal of Child Health Care;1997-02
2 XU TIE;HU SHU-TSU(Shanghai Institute of Physiology,Academia Sinica,Shanghai200031);RELATIONSHIP BETWEEN CENTRAL β-ENDORPHINS AND SEROTONIN SYSTEMS IN MECHANISM OF HYPOXIC VENTILATORY REGULATION[J];Acta Physiological Sinica;1991-06
3 Xiaolei Wang, et al (Pediatric Dept. of the Third Municipal Hospital of Chengdu);EFFECT OF ASPHYXIA UPON NEONATAL'S T-CELL SUBSETS AND ERYTHROCYTES IMMUNE FUNCTIONS[J];The Journal of Neonatology;1996-04
4 Jiang Jing, Yao Yujia, Li Weiru, et al. Department of Pediatrics, Second Hospital, West China University of Medical Sciences, Chengdu 610041;The protective effect of nimodipine on hypoxic ischemic encephalopathy of newborn piglets[J];Chinexe Journal of Pediatrics;1997-02
5 Liu Enmei, Li Chengrong, Yang Xiqiang, et al. Children′s Hospital, Chongqing Medical University Chongqing 400014;Apoptosis of human cord blood mononuclear cells and its regulators[J];Chinexe Journal of Pediatrics;1998-06
6 Gu Wenping, Yang Qidong, Ouyang Shan. The Institute of Neurology, Xiang Ya Hospital, Hunan Medical University, Changsha 410008;A dynamic study on platelet intracellular calcium and regional brain calcium in rabbit cerebral ischemia[J];CHINESE JOURNAL OF CERIATRICS;1997-05
7 Lin Jiayou; Shen Yafang; Gao Yang; Li Li (Institute of Basic Medical Sciences, CAMS and PUMC, Beijing 10005);β-Endorphin Enhances IL-2 and IFN-Υ Gene Expression in Human Blood Mononuclear Cells[J];ACTA ACADEMIAE MEDICINAE SINICAE;1997-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved