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《CHINESE JOURNAL OF IMMUNOLOGY》 1996-02
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IMMUNE TUMOR-INHIBITION OF LYCIUM BARBARUM POLYSACCHARIDE ON S_180-BEARING MICE

Liu Jielin; Zhang Linghua;Qian Yukun.(Department of Immunology,Beijing Medical University , Beijing 100083.Department of Immunology,Guiyang Medical College,Guiyang 550004)  
Lycium barbarum polysaccharide(LBP) is the biological activated substance which has widely immunological effect. Taking S180-bearing Balb/c mice as an animal model and systematically investigated that effect of LBP on tumor weight and immunologic function of S180-bearing mice in vivo. The results showed that LBP could dose-dependently decrease tumor weight and promote the numbers of splenocyte, proliferation of activated T cells, NK activity and TNFβ levels in S180-bearing mice. So in tumor-bearing mice, it was suggested that the mechanism of tumor-inhibition by LBP was due to enhance the cellular immunity.
【Fund】: 美国中华医学基金会奖学金(CMB)
【CateGory Index】: R285.5
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