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《Journal of Chongqing Medical University》 2011-09
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Genetic polymorphism of seventeen Y-chromosomeal STR loci in XinJiang Bazhou Uygur population

CHEN Hui-jin 1,PU Hong-wei 2,HU Jia3,WANG Wei3,ZHANG Li-ping1 (1.Biochemistry and Moleculor Biology Section,Foundation Medical College,Xinjiang Medical University; 2.Pathology Section,Foundation Medical College,Xinjiang Medical University;3.Criminal Science and Technology Institute,Xinjiang Bazhou Police)  
Objective:To investigate the allelic and haplotype frequency distribution of seventeen short tandem repeat loci of Y chromosome in Xinjiang Uygur population in Bazhou.Methods:The template DNAs were extracted from blood samples of 149 unrelated Uygur male individuals,and seventeen Y-STR loci were amplified by the AmpFlSTR YfilerTM.The PCR products were analyzed and genotyped with ABI3130XL Sequencer.Results:The values of genetic diversity of DYS456,DYS389Ⅰ/Ⅱ,DYS390,DYS458,DYS19,DYS385a/b,DYS393,DYS391,DYS439,DYS635,DYS392,Y-GATA-H4,DYS437,DYS438,and DYS448 were between 0.4 982 and 0.9 485.A total of 148 different haplotypes were observed,and the value of genetic diversity of haplotypes was 0.99 986.Conclusion:The 17 Y-STR loci in Xinjiang Uygur population in Bazhou are highly polymorphic and suitable for paternity testing and paternal genetic lineage evolution.
【CateGory Index】: R394
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