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《重庆医科大学学报》 1995-04
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A STUDY ON CARDIAC FUNCTION IN EARLY ALLOXAN DIABETIC RABBITS

Wang Yi;et al. (Dept.of medieine ,the Fiist hospital)  
he early changes of cardiac function were studied in alloxan dialbetic rabbits in comparison with nomlal con-trols.After the onset of dialsetes for 4 weeks, left ventricular function indices including the peak pressure of leftventricule(Peak),the end diastolic pressure(EDP)the isovolumic contraction pressure(IP),the Peak negative -dp/dt max,(-Smax)and the area of lieart Working cycle(Area)were all significantly lower then those of normalcontirols(IP,-Smax,P 0.005);Area(P 0.05)EDP,P(0.001)The results suggested that eraly decrease of leftventricular contraction and relaxation mdy be relaed to abnomal metabolism and diabetic cardiomyopathy.
【CateGory Index】: R587.1
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