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《Journal of Fishery Sciences of China》 2008-01
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Comparative study on the bioactive components and immune function of three species of sea cucumber

ZHAO Qin,WANG Jing-feng,XUE Yong,WANG Yi,GAO Sen,LEI Min,XUE Chang-hu (Food Science and Engineering College,Ocean University of China,Qingdao 266003,China)  
Sea cucumber has been proved as a source of substance rich in nutritional components and biological activity. Sea cucumber saponins and triterpene glycosides,commonly known as holothurins,have drawn attention because of their wide spectrum of biological effects such as antifungal,cytotoxic,hemolytic,cytostatic and immunomodulatory activities. In this study,the bioactive components of Isostichopus badionotus,Isostichopus fuscus and Cucumaria frondosa and their function on immune regulation were determined by chemical analysis and immunological methods. The contents of polysaccharide,triterpene glycosides and amino acids in body wall were measured and compared,and their immune regulation were investigated with the model mice in normal and in immunodepression induced by hydrocortisone. The results showed that I. fuscus had the highest content of polysaccharide in the body wall among these three species of sea cucumber. The contents of triterpene glycosides,total amino acids,drug-effective amino acids and delicious amino acids are higher in C.frondosa than in the others. In normal mice,all three kinds of sea cucumber could increase thymus/body weight value,heighten delayed hypersensitivity level (P0.05 or P0.01) and the ability of macrophages for carbon particle clearance (P0.05 or P0.01). In hypoimmune mice,they all could antagonize the decline of thymus/body weight value induced by hydrocortisone (P0.05 or P0.01),increase hemolysin content (HC50) (P0.05 or P0.01),spleen lymphocyte transformation (P0.05 or P0.01) and the ability of macrophages for carbon particle clearance (P0.05 or P0.01). C.frondosa had the most remarkable effects in HC50 and phagocytic index (SNK,P0.05). Triterpene glycoside from another kind of sea cucumber C.japonica was found to stimulate phagocytosis and production of IL6 and TNF-?,and increase the number of antibody producing cells. At the same time,the preparation did not affect the delayed-type hypersensitivity and cytokine IL12 and IFN-γ release. This suggests triterpene glycoside in sea cucumber could promote humoral immunity and non-specific immunity. Sea cucumbers have high content of Gly,Glu and Arg in body wall. Gly can stimulate production and release of IL-2 and B cell antibody,and enhance phagocytosis. Gly and Glu are essential materials for cell to synthesize glutathione which can stimulate activation and proliferation of NK cell. Arg can enhance cell immunity by promoting activation and proliferation of T-cell. It is suggested that these three species of sea cucumbers all have remarkable function in immune regulation. They can both promote immune function by cell immunity and non-specific immunity in normal mice and promote immune function by cell immunity,humoral immunity and non-specific immunity in immunodepression mice. The significant effect on immune regulation of C.frondosa correlated to its higher contents of triterpene glycoside and active amino acids in all probability.
【Fund】: 国家自然科学基金项目(30471319);; 新世纪优秀人才支持计划项目(NCET-04-0642);; 中国海洋大学海水养殖教育部重点实验室开放课题.
【CateGory Index】: S917.4
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【References】
Chinese Journal Full-text Database 10 Hits
1 LI Dan-tong,CHANG Ya-qing,WU Zhen-hai,CHEN Wei,WANG Jun-ya,CHEN Guo-dong(Key Laboratory of Mariculture & Biotechnology,Agriculture Ministry,China,Dalian Fisheries University,Dalian 116023,China);Analysis of Nutritive Composition of Body Wall in Wild Sea Cucumber Apostichopus japonicus Selenka at Zhangzi Island in Spring and Autumn[J];Fisheries Science;2009-07
2 DING Jin-feng,SU Xiu-rong,LI Yan-yan,GAO Xiang,YUE Fu-peng,JIANG Xin(College of Life Science and Biotechnology,Ningbo University,Ningbo 315211,China);Immune Functions of Jellyfish Collagen Peptide[J];Fisheries Science;2011-06
3 LI Xia,ZHOU Hai-yan,QIN Yan-jie,XIN Jun-hong(Key Laboratory of Marine Bio-resourses Sustainable Utilization in Liaoning Province's University,Dalian Ocean University,Dalian 116023,China);Microstructure and ultrastructure of body wall in sea cucumber Apostichopus japonicus[J];Journal of Dalian Ocean University;2010-04
4 SUN Weihong1,2 LENG Kailiang2 LIN Hong1 XING Lihong2 NING Jinsong2 WANG Zhijie2 ZHAI Yuxiu2 WANG Zewen1 MIAO Junkui2 LI Xiaochuan2 HAN Xianqin2 LIU Qi2(1.Department of Food Science and Engineering,Ocean University of China,Qingdao 266100,China;2.Yellow Sea Fishery Research Institute,Chinese Academy of Fishery Sciences,Qingdao 266071,China);Analysis and Evaluation of Chief Nutrient Composition in Different Parts of Stichopus japonicus[J];Chinese Journal of Animal Nutrition;2010-01
5 CUI Jing1, LI Tai-Wu2, SU Xiu-Rong1, LI Ye1, XU Jing3, ZHOU Jun1, YING Qi1, WANG Zhong-Hua1, LI Song-Wei1 (1. Faculty of Life Science and Biotechnology, Ningbo University, Ningbo, 315211; 2. Ningbo City College of Vocational Technology, Ningbo, 315100; 3. Wenzhou Vocational & Technology College, Wenzhou, 325035);CONSTRUCTION OF cDNA LIBRARY WITH APOSTICHOPUS JAPONICUS CULTURED IN THE SOUTH AND SEQUENCE ANALYSIS OF ITS TROPOMYOSIN GENE[J];Oceanologia Et Limnologia Sinica;2010-06
6 JIAO Jian,KANG Hai-yan(Dalian Haiyantang Biology Co.,Ltd.Dalian 116021,China);Studies on losses of some functional components during traditional processing trepang from Apostichopus japonicus[J];Chinese Journal of Marine Drugs;2010-04
7 ZHAO Ling1,2,YIN Bang-zhong1,LIU Qi1*,CAO Rong1,WEI Yu-xi2*(1.Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences; National R&D Branch Center For Sea Cucumber Processing,Qingdao 266071,China; 2.Biological Department of Qingdao University,Qingdao 266071,China);Comparative study on antioxidation activity of polypeptides from four kinds of sea cucumbers[J];Chinese Journal of Marine Drugs;2012-02
8 Tao Lin,Wu Zhongchen,Zhang Pengyan,Li Lianghong,Liu Chang(School of Space Science and Physics,Shandong University at Weihai,Weihai 264209,China);Rapid identification of dried sea cucumber products from different geographical areas by near-infrared spectroscopy[J];Transactions of the Chinese Society of Agricultural Engineering;2011-05
9 XIA Chang-Ge 1,3,CUI Jing 1,WANG Zhong-Hua 1,LI Cheng-Hua 1,ZHOU Jun 1,LI Ye 1,ZHANG Chun-Dan 1,LI Tai-Wu 2,SU Xiu-Rong 1 (1.School of Marine Science,Ningbo University,Ningbo,315211;2.Ningbo City College of Vocational Technology,Ningbo,315100;3.Xinlicheng Reservoir Management Bureau in Changchun,Changchun,130119);PROKARYOTIC EXPRESSION OF TROPOMYOSIN GENE FROM SOUTH CULTURED SEA CUCUMBER APOSTICHOPUS JAPONICUS[J];Oceanologia et Limnologia Sinica;2013-01
10 LIU Zhi-Dong1,WANG Jing-Feng2,WANG Yu-Ming2,XUE Yong2,ZHAO Qin2,XUE Chang-Hu2(Ocean University of China 1.College of Marine Life Sciences;2.College of Food Science and Technology,Qingdao 266003,China);The Effects of Squid Ink Glycosaminoglycan on the Immune Function of Mice[J];Periodical of Ocean University of China;2009-S1
【Citations】
Chinese Journal Full-text Database 9 Hits
1 YAN Bing, LI Ling *, YI Yang-hua, TANG Hai-feng, SUN Peng, ZHANG Shu-yu (Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, China);Study on bioactive triterpene glycosides of sea cucumber Holothuria scabra Jaeger[J];Academic Journal of Second Military Medical University;2005-06
2 Liu Hongying (College of Fisheries, Agriculture University of Hebei, Qinhuangdao 066000 ,China) Xue Changhu Li Zhaojie Ou Changrong Cai Yaopiao Zhao Xue Xu Jiachao (College of Fisheries, Ocean University of Qingdao, Qingdao 266003,China);Spectrophotometric Determination of Fucoidanin Laminaria Japonica with Methylene Blue[J];Journal of Ocean University of Qingdao;2002-02
3 WANG Jing-Feng~1,WANG Yi~1,ZHAO Lin~2,PANG Long~1,XUE ChangHu~1(1.College of Food Science and Engineering,Ocean University of China,Qingdao 266003,China;2.Department of Traditional Chinese Medicine,456th Hospital of People's Liberation Army,Jinan 250031,China);Effects of Apostichopus japonicus on Antitumor and Immune Regulation in S_(180) Bearing Mice[J];Periodical of Ocean University of China;2007-01
4 CUI Feng-xia,XUE Chang-hu,LI Zhao-jie,DONG Ping,XUE Dong-mei(College of Food Science and Technology,Ocean University of China,Qingdao 266003,China);Extraction and the physical and chemical characterization of collagen in Stichopus japonicus[J];Journal of Fisheries of China;2006-04
5 JIANG Jian, YANG Bao-ling, TAI YangBioengineering Department of Dalian Nationalities University, Dalian 116600, China;Studies on resources and bioactive substances of sea cucumber[J];Letters in Biotechnology;2004-05
6 SHEN Ming (Nanjing University of TCM, Nanjing 210029, China);Investigation on Component and Pharmacology of Sea Cucumber[J];Chinese Traditional Patent Medicine;2001-10
7 Peng Xi, You Zhong-yi, Wang Shi-liang (State Key Laboratory of Trauma, Burns and Combined Injury, Institute of Burns Research, Southwest Hospital, the Third Military Medical University, Chongqing 400038, China);Effect of Arginine on Immunologic Function: Research Advances and Clinical Application[J];Chinese Journal of Clinical Nutrition;2005-06
8 Wang Tingfu, Meng Zhengmu 1 Hongze People′s Hospital, Hongze 233100; 1Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009;Experiment for Immunity Effects of Ginsenoside Rg 3[J];JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY;1999-02
9 GAO Li-ping,LIU Hua,FENG Yun-fang (College of Materials and Textiles,Zhejiang Institute of Science and Technology,Hangzhou 310027,China);Determination of Total Saponin Content in Panax Ginseng[J];Journal of Zhejiang Institute of Science and Technology;2002-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Xiao_qiu, WANG Rong_xian, TIAN Qing_wei(Institute of Radiation Medicine Chinese Academy of Medical Sciences, Tianjin 300192 , China);MUTAGENICITY RESEARCH OF No.Ⅱ DRUG[J];Carcinogenesis,Teratogenesis and Mutagenesis;2003-01
2 LIN Fei1,LIANG Yi1,LU Lian1,YANG Wen-jie2,YANG Yan-hua2(National Institute for the Control of Pharmaceutical and Biological Products,Beijing 100050;2.Institute of Nutrition and Food Safety,Chinese Center for Disease Control and Prevention,Beijng 100050,China);Selenium-enriched Garlic on the Gastric Juice Components and Upper Gastrointestinal Tract Stimulation in Experimental Animal[J];Carcinogenesis,Teratogenesis & Mutagenesis;2008-04
3 CHEN Yi-cun,CAI Cong-yi,JI Bin,GAO Fen-fei,ZHANG Yan-mei,HUANG Zhan-qin,BAI Xue-ting,SHI Gang-gang(Department of Pharmacology,Medical College,Shantou University,Shantou 515041,Guangdong,China);Combination of scopoletin and hesperetin from Ipomoea Stolonifera using uniform design experimentation[J];Carcinogenesis,Teratogenesis & Mutagenesis;2010-03
4 WANG Yan-ping1,CHEN Yan2(1.Department of Chemistry and Chemical Engineering,Hefei Normal University,Hefei 230061,China; 2.Anhui Institute of Gedogical Experiment,Hefei 230001,China);Four Aza-crown Ether Complexes of Copper Affect on the Level of Carbon Clearance of Immunosuppressed Mice[J];Journal of Hefei Normal University;2011-06
5 GAO Gui-zhen1,2,CHEN Qun2,LI Xu-liang2(1.Biochemistry Analysis Laboratory,Suzhou College,Suzhou 234000,China;2.State Key Laboratory of Pharmaceutical Biotechnology,College of Life Science,Nanjing University,Nanjing 210093,China);Study on the Pharmacology nature of sulfated pachymaran[J];Journal of Anhui University(Natural Sciences);2009-06
6 Wang Guimei et al.(High latitude and Cold Weather Crops Institute,Shanxi Academy of Agricultural sciences,Datong 037008,China);Study on Tissue Culture Technology of Platycodon grandiflorum[J];Anhui Agricultural Science Bulletin;2012-07
7 Song Shuhui et al (National Engineering Research Center for Vegetable, Beijing 100089);Research on the Ability of Anti oxygen Free Radicals of the Cabbage Vegetables[J];Journal of Anhui Agricultural Sciences;1999-06
8 HE Yong-ming et al(Department of Animal Medicine,Foshan University of Science and Technology,Foshan,Guangdong 528000);Efficacy Test on Yinqiao Detoxification Granules against Experimental Colibacillosis in Ducks[J];Journal of Anhui Agricultural Sciences;2008-03
9 LI Li et al (College of Life Science,Henan Normal University,Xinxiang,Henan 453007);Study on the Effects of Sophora alopecuroides L.on the Immune Function of Mice[J];Journal of Anhui Agricultural Sciences;2008-10
10 CAO Si-jun et al (Tianhuang Town Government of Zoucheng City Shangdong Province, Zoucheng,Shandong 273506);Diagnosis and Treatment of Yeast Mastitis in Dairy Cattle[J];Journal of Anhui Agricultural Sciences;2008-21
China Proceedings of conference Full-text Database 10 Hits
1 ;Study on the Functional Effect of Chufa Functional Component[A];[C];2004
2 TANG Hong-mei1, QIU Zhen-wen1 ,LI De-tang2, KUANG Zhong-sheng2,YAN Xue2 (1 The First Affiliated Hospital of Guangzhou University of TCM ,Guangzhou 510405,china; 2 Guangzhou University of TCM ,Guangzhou ,510405,china);Mechanism Research of Changjian Fang Intervention on SP and CGRP in Model Rats of Diarrhea-Irritable Bowel Syndrome[A];[C];2010
3 Li Jing1,Zhu Yi2,Chen Guo-biao1,Huang Ling1 (1.Dept.of Pharmacology,Chongqing University of Medical Sciences,Chongqing 400016,China;2.Dept.of Pharmacology,the Institute for Drug Control of Hainan Province,Haikou 570216 China);Study on Antidiarrheal Effects of Total Flavonoids from the roots of Pongamia pinnata[A];[C];2007
4 CHU Mei-na~1,ZHU Yi~2,Yang Jia~1 (1.Chongqing Univercity of Medical Sciences,Chongqing 400016,China.2.Hainan Provincial Institute for Drug Control,Haikou 570216,China);Analgesic and Anti-inflammatory Effects of Total Alkaloids from Stephania hainanensis H.S.Lo et Y.Tsoong and it's Acute Toxicity Study[A];[C];2010
5 Siriguleng Zhang - Shuyu Temuer (Inner Mongplia Medical College, Hohhot 010059 China);Study of the sudorific effect of the daoguleebusi - 7 capsule[A];[C];2006
6 Feng Jian-hua,Mu Yan-ling,Xu Shu-lan,Zhu Yan,Cui Shu-xiang (Shandong Academy of Medical Scienses, Jinan, 250062);Protective effects of naomaixin granule on experimental cerebral ischemia in rats[A];[C];2005
7 LI Bao-qiu , WANG Ge, ZHAO Hua, ZHAO Yan-biao, (Toxicology Research Department of SDU, Jianan 250014, China; Shandong Yuanlong Biotechnology Co., Ltd, Jinan 250010, China; Shandong Hongli Laboratory Animal Experiments Co., Ltd, Jinan 250101, China);Rapid dissolution affects of recombined reteplase on blood clots induced in vivo[A];[C];2005
8 ;小儿解热栓的药理筛选[A];[C];2006
9 LI Wen-xia1, YAN Yan2, CHEN Zhong-guang2, CONG Ren-huai2, YE Xiao-chuan2*(1 Department of Chemistry, 2 College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074,China);Study on Anti-inflammatory effects and mechanism of activity sections of Smilax china L.[A];[C];2006
10 ZHANG Ling ZHANG Dao-ying DUN Zhu LIU Ya li [Key Laboratory of Modern Preparation of TCM,Ministry of Education(Jiangxi University of TraditionaL Chinese Medicine)Jiangxi Nanchang 330004 Tibetan Traditional Medicine college,Xizang Lasa 850000];The Anti-inflammatory and Analgesic Effects of Tibetan Drug Pyrethri tatsienensis[A];[C];2007
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Hou Yanjun2 Xie Jun1 Zhou Qunlan1 Liu Bo1 Xu Pao1 (1 Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi,Jiangsu 214081; 2 College of Fisheries in Wuxi, Nanjing Agricultural University, Jiangsu Wuxi 214081);Summarization of Research onFish and shrimp body color[J];Anhui Agricultural Science Bulletin;2007-14
2 WANG Ting-xiang et al(The Third People Hospital in Baoding,Baoding, Hebei 071000);Effect of Laminarina japonica Polysaccharides on the Intestinal Mucosal Secretary SIgA in Mice[J];Journal of Anhui Agricultural Sciences;2009-12
3 YangLiansongetal(RiceResearchInstitute,AnhuiAcademyofAgriculturalSciences,Hefei230031);AStudyonAntimicrobialActionandAntisepticEffectofTeaPolyphenolsonSomeCommonPutrefiedMicrobes[J];JOURNAL OF ANHUI AGRICULTURAL SCIENCES;1996-04
4 Hu Renjie Yu Suping Jiang Hui Wang ShixianTianjin Institute of Medical and pharmaceutical Sciences, Tianjin 300070;The inhibitory effect of SJAMP combined with cortisone on murine solid tumors[J];CHINESE JOURNAL OF CANCER;1997-06
5 XU Yun-jie,FANG Re-jun (College of Animal Science and Technology,Hunan Agriculture University,Changsha 410128,China);Function of Anti-Fatigue of Branched-Chain Amino Acids[J];Amino Acids & Biotic Resources;2008-01
6 DIAO Quan-ping,HOU Dong-yan,HUI Rui-hua,LI Tie-chun,GUO Hua(Department of Chemistry,Anshan Normal University,Anshan Liaoning 114007,China);Analysis on Fatty Acids in Sea Cucumbers by Gas Chromatography-Mass Spectrometry[J];Journal of Anshan Normal University;2008-06
7 Pan Jiahua,Lou Wanling,Chen Lanju,Ding Zhouzhi,Li Huamin (Department of Pediatrics,Affiliated Hospital of Bengbu Medical College,Anhui 233004 );Thymic peptides modulating side effect of hydrocortisone on immune function[J];JOURNAL OF BENGBU MEDICINAE COLLEGE;1999-01
8 PENG LING,YU ZHUANG,SONG YANG(Department of Oncology,The Affiliated Hospital of Qingdao University Medical College,Qingdao 266003,China);EFFECT OF STICHOPUS JAPONICUS ACIDIC MUCOPOLYSACCHARIDE ON PROLIFERATION AND DIFFERENTIATION OF Hela CELLS[J];Acta Academiae Medicinae Qingdao Universitatis;2008-03
9 ZHANG Wei-Zhu 1,4 , WU Xin-Zhong 2 , WANG Ming 3 1. Department of Chemistry and Biology, Chuzhou University, Chuzhou 23900, Anhui, China 2. College of Animal Sciences, Zhejiang University, Hangzhou 310029, China 3. College of Veterinary Medicine, China Agricultural University, Beijing 100094, China 4. South China Sea Institute of Oceanology, the Chinese Academy of Sciences, Guangzhou 510301, China;Surface and ultrastructural characterization of the haemocytes in the scallop Argopecten irradians[J];Acta Zoologica Sinica;2005-03
10 ZHANG Wei-Zhu 1,3, WU Xin-Zhong 2**, LI Deng-Feng1,SUN Jing-Feng11. South China Sea Institute of Oceanology, the Chinese Academy of Sciences, Guangzhou 510301,China2. College of Animal Sciences, Zhejiang University, Hangzhou 310029,China3. Department of Chemistry and Biology, Chuzhou College, Chuzhou 390000, Anhui,China;Immunological functions of blood cells in the scallop Chlamys farreri[J];Acta Zoologica Sinica;2005-04
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 HAN Qiu-ju et al(School of Environmental and Biological Engineering,Liaoning Shihua University,Fushun,Liaoning 113001);Extraction and Purification of Polysaccharides in Sea Cucumber[J];Journal of Anhui Agricultural Sciences;2012-14
2 ZHOU Chan ZHU Yong XU Shui (College of Biotechnology,Southwest University,Chongqing 400715,China);Primary Culture Methods for Invertebrate Cells[J];Chinese Journal of Animal Nutrition;2011-02
3 JIANG Xiamin PENG Ruibing LUO Jiang GAO Xiuzhi JIANG Xiaomin(College of Ocean,Ningbo University,Ningbo 315211,China);Analysis and Evaluation of Nutrient Composition in Different Tissues of Wild Sepia lycidas[J];Chinese Journal of Animal Nutrition;2012-12
4 QIN Yan-jie,LI Xia,ZHANG Hui-min,WANG Xue(Key Laboratory of Mariculture & Stock Enhancement in North China's Sea,Ministry of Agriculture,Key Laboratory of Marine Bio-resources Restoration and Habitat Reparation in Liaoning Province,Dalian Ocean University,Dalian 116023,China);Construction and analysis of subtractive cDNA library of recovery body wall in sea cucumber Apostichopus japonicus[J];Journal of Dalian Ocean University;2013-03
5 JI Cheng-Long1, 2, SUN Guo-Hua1, YANG Jian-Min1, SONG Zhi-Le3, LIU Xiang-Quan1, WANG Wei-Jun1 (1. Shandong Marine Fisheries Research Institute, Yantai, 264006; 2. School of Fishery and Life Science, Shanghai Ocean University, Shanghai, 201306; 3. Zhifu Fishery Technical Extension Station, Yantai, 264001);CONSTRUCTION AND ANALYSIS OF THE SUBTRACTED cDNA LIBRARY OF APOSTICHOPUS JAPONICUS (SELENKA) UNDER HIGH TEMPERATURE STRESS[J];Oceanologia et Limnologia Sinica;2011-01
6 QIAN Yao-sen1,ZHENG Xiao-dong1,WANG Pei-liang2,LI Qi1(1.Fisheries College,Ocean University of China,Qingdao 266003,China;2.Mashan Group Co.Ltd.,Weihai 264319,China);Analysis and evaluation of nutritive composition of Octopus minor in Lake Swan[J];Marine Sciences;2010-12
7 WANG Zhe-ping LIU Qi CAO Rong YIN Bang-zhong (Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,National R&D Branch Center for Sea Cucumber Processing,Qingdao 266071);Effect of temperature on the changes of structure and molecular weight of Apostichopus japonicus collagen[J];Progress in Fishery Sciences;2011-06
8 BAO Yu-ming,HOU Hu,QIAO Ruo-jin,TAO Yu,LI Zhi-hao,LI Ba-fang*(College of Food Science and Technology of Ocean University of China,Qingdao 266003,China);Preliminary configuration identification and immuno-enhancing activity of Haliotis discus hannai Ino visceral glycoprotein[J];Chinese Journal of Marine Drugs;2012-04
9 Li Ye1,2,*Wang Lianzhu2,Li Xiaoqing1,2,Zhu Wenjia2,Song Chunli2(1.College of Food Science and Engineering,Ocean University of China,Qingdao,Shandong 266003,China; 2.Institute of Yellow Sea Fishery,The Chinese Academy of Fishery Sciences,Qingdao,Shandong 266071,China);A Comparative Study on Determination of Salt Content in Sea Cucumber Product[J];Academic Periodical of Farm Products Processing;2011-11
10 Liu Qi,Cao Rong,Wang Lianzhu,Yin Bangzhong(Yellow Sea Fishery Research Institute,Chinese Academy of Fishery Sciences,National R&D Branch Center for Sea Cucumber Processing,Qingdao,Shandong 266071,China);Effect of Soaking Parameters on Dried Sea Cucumber Processing[J];Innovational Edition of Farm Products Processing;2010-11
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Hu Renjie Yu Suping Jiang Hui Wang ShixianTianjin Institute of Medical and pharmaceutical Sciences, Tianjin 300070;The inhibitory effect of SJAMP combined with cortisone on murine solid tumors[J];CHINESE JOURNAL OF CANCER;1997-06
2 GOU Jun 1, YOU Zhong yi 2,PENG Xi 2, et al. (1 Laboratory Center;2.Institute of Burn Research,the Third Military Medical University, Chongqing 400038,China);The toxicity experiments of arginine acetate[J];Chongqing Medical Journal;2004-03
3 PENG Xi, YOU Zhong yi, WANG Pei, ZHOU Xing, LIU Jing, WANG Shi liang (Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Effects of arginine-supplemented enteral nutrition on immunological function in severe burned rabbits[J];Parenteral & Enteral Nutrition;2002-03
4 TANG Hai Feng 1,YI Yang Hua 1,YAO Xin Sheng 2,LIN Hou Wen 3,ZHANG Shu Yu 1,WU Jiu Hong 4 (1. Research Center for Marine Drugs,College of Pharmacy,Second Military Medical University,Shanghai 200433,China; 2. Department of Traditional Chinese Ph;Using conidia of Pyricularia oryzae screening for bioactive portions from marine organisms[J];Academic Journal of Second Military Medical University;2002-03
5 YAN Bing, LI Ling *, YI Yang-hua, TANG Hai-feng, SUN Peng, ZHANG Shu-yu (Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, China);Study on bioactive triterpene glycosides of sea cucumber Holothuria scabra Jaeger[J];Academic Journal of Second Military Medical University;2005-06
6 ZHAO Cang-bi, HUANG Yu-dong, LI Yan-hui(Dept. of Applied Chemistry, Harbin Institute of Technology, Harbin 150001,China, );Extraction of collagen from cattle tendons[J];Journal of Harbin Institute of Technology;2004-04
7 Cen Ying, Luo Xusong,Ren Linsen, Liu Xiaoxue.Department of Burn and Plastic Surgery, The First Affiliated Hospital, WCUMS,Chengdu 610041;Effect of Arginine on Deep Partialthickness Burn in Rats[J];JOURNAL OF WEST CHINA UNIVERSITY OF MEDICAL SCIENCES;1999-02
8 Chan Judi, Fan Huizeng, Xing Ruining , (Institute of Medical &. Pharmaceutical Science, Tianjin, 300070);STUDIES ON THE ISOLATION OF THE ACIDIC POLYSACCHARIDES IN STICHOPUS VARIEGATUS[J];Chinese Journal of Marine Drugs;1994-01
9 Wu Pingru; Fang jinrui; Huang Weizhen; et al.(Fujian Institute of Oceanology, Xiamen 361012);STUDIES ON THE CHEMICAL CONSTITUENT FROM SEA CUCUMBER MENSAMARIA INTERCEDENS──Ⅱ.PMI-1, A NOVEL FUCOSAN[J];CHINESE JOURNAL OF MARINE DRUGS;2000-02
10 WT5BZ] Guan Huashi,Geng Meiyu,Wang Changyun (Qingdao Ocean University,Qingdao 266003);MARINE DRUGS IN CHINA TOWARDS 21ST CENTURY[J];CHINESE JOURNAL OF MARINE DRUGS;2000-04
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