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《Chinese Journal of Experimental Traditional Medical Formulae》 2003-06
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Experimental Study of Semen Astragali Complanati Extract on the Lipid-Modifying and Liver-Protective Effects

XIE Mei-lin,ZHU Lu-jia,LIU Chun-yu,ZHAO Xi-lin,XUE Jie,GU Zhen-lun (School of Medicine,Soochow University,Suzhou Institute of Chinese Materia Medica,Jiangsu Suzhou 215007,China)  
Objective:To observe the lipid-modifying and liver-protective effects of semen astragali complanati extract A and B.Methods:Male hyperlipidemic rats were induced by feeding with fat milk.The serum TC,TG,HDL-C,LDL-C and coefficient of hepatic weight were measured after administration of semen astragali complanati extract for 20 days.The levels of serum ALT and AST of the mice injured by ip 0.07% CCl 4 0.1ml/10g were examined after mice were given semen astragali complanatix extract for 14 days.Results:In semen astragali complanati extract A and B groups,the levels of serum TC,TG and LDL-C were lower than those in the hyperlipidemic group,while serum HDL-C was increased.The serum ALT and AST levels in semen astragali complanati extract groups were lower than those in liver-injured group as well.Conclusion:Semen astragali complanati extract A and B possessed the obvious lipid-modifying and liver-protective effects,and the effects of both extracts were basically similar.
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 3 Hits
1 WANG Li1,LIU Jing2,YANG Jian-xiong1(1 College of Life Science,Shaanxi Normal University,Xi′an 710062,Shaanxi, China; 2 Department of Biology,Shaanxi Education College,Xi′an 710061,Shaanxi,China);Studies on antioxidant activities of ethanoic extract from defatted Semen astragali complanati in vitro[J];Journal of Shaanxi Normal University(Natural Science Edition);2008-04
2 SUN Li-bing1,2,WANG Wei-ping2,GU Zhen-lun1,3,GUO Ci-yi1,3(1.Suzhou Institude of Chinese Metrial Medica,Jiangsu Suzhou 215007,China;2.Dept of Biochemistry and Molecular Biology,Medical Colleage,Soochow University,Jiangsu Suzhou 215123,China;3.The Hong Kong Association for Health Care,Hong Kong 999077,China);Protection of Flavonoids From Astragalus Complanatus on Hepatic Fibrosis Induced by Carbon Tetrachloride in Mice[J];Suzhou University Journal of Medical Science;2010-01
3 ZHANG Jian-jun~1, YAN Xing-li~1, ZHANG Yu-jie~1, WANG Yu-ping~2, ZHANG Qiu-ju~1, ZENG Feng-ying~1, LI Wei~1, OU Li-na~1(1. Beijing University of Chinese Traditional Medicine, Beijing 100029, China;2. Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences andPeking Union Medical College,Beijing 100094, China);Determination of complanatoside A in Semen Astragali Complanati by HPLC[J];China Journal of Chinese Materia Medica;2005-08
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 XIONG Xiao-juan~1, CHEN Wu~1, XIAO Xiao-hua~2, XU Li-ying~2, CUI Jang-long~3 (1.Yichun University,Yichun Jiangxi 336000,China; 2 Jiangxi Institute of Materia Medica,Nanchang 330029,China; 3.The First People's Hospital of Yichun District,Yichun Jiangxi 336000,China);The Comparative Protective Effect of Ursolic Acid and Oleanolic Acid on Experimental Liver Injury in Mice[J];Journal of Jiangxi Normal University (Natural Sciences Edition);2004-06
2 LI Su ting, YANG He mei, SHI Yan hua,et al (Chengde Medical College, Hebei Chengde 067000,China);PROTECTIVE EFFECTS OF SCUTELLARRIA BAICALENSIS STEM-LEAF TOTAL FLAVONID ON CARBON TETRACHLORIDE ACUTE HEPATIC INJURY IN MICE[J];Journal of Chengde Medical College;2003-04
3 LI Zhi xiao 1,HUANG Cheng gang 2,CHEN Yao zu 1,2 \j (1 National Laboratory of Applied Organic Chemistry,Lanzhou University,Lanzhou 730000,China; 2 Department of Chemistry,Zhejiang University,Hangzhou 310027,China);Studies on polysaccharide from Sophora subprosrata[J];ACTA BOTANICA BOREALI-OCCIDENTALIA SINICA;2000-02
4 ZHAO Chun-jing, WEI Lai (Department of Pharmaceutics, The Second Affiliated Hospital of Chongqing University of Medical Sciences, Chongqing 400010, China);Protective effects of puerarin on CCl_4-induced acute hepatic injury in rats[J];Acta Academiae Medicinae Militaris Tertiae;2005-07
5 XIN Nian, XIONG Jian-xin, HAN Shu-ying, ZHU Li-sha, LIU Shu-mei, CHU Jin-xiu (Department of Pharmacology, North China Coal Medical College,Tangshan 063000,China);Protective effect of total flavonoids of buckwheat seed on acute hepatic injury by carbon tetrachloride[J];Acta Academiae Medicinae Militaris Tertiae;2005-14
6 ZHANG Yan Jun 1,XIA Tian 2,ZHAO Jian Bin 2 1Oncology center, 2Department of Traditional chinese Medicine,Xijing Hospital, Fourth Military Medical University,Xi'an 710033;Effects of Matrine on the differentiation of SMMC 7721 cell lines[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;1998-03
7 ZHANG Hong-feng , XU Man-yan, WANG Yao-fa(Department of Biology, East China Normal University, Shanghai 200062, China);Protective Effects of Lycium Bararum Polysaccharides on Carbon Tetrachloride and High Glucose Damaged Hepatocytes[J];Journal of Eastchina Normal University(Natural Science);2004-03
8 ZHAO Zhi-min,LI Chao-jun(Henan Traditional Chinese Medicine College,Zhengzhou Henan 450008,China);Treatment Observation of Shaoyaogancaotang Modified on 36 Cases of Dry Eye[J];Journal of Henan Medical College for Staff and Workers;2006-03
9 He Guixia, Li Ling, Xiao Jinren, et al (Faculty of Pharmacetics, TCM Univ. of Hunan, Changsha 410007);The therapeutic effects of Tengcha Flavonids on hepatic injury induced by CCl_4 among mice[J];Journal of Hunan Traditional Chinese Medicine University of Hunan;2004-04
10 Zhang Mingyuan, et al;Protective effects of ligustrazini on experimental liver injury in mice[J];HEILONGJIANG MEDICINE AND PHARMACY;2000-03
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 WANG Li1,LIU Jing2,YANG Jian-xiong1(1 College of Life Science,Shaanxi Normal University,Xi′an 710062,Shaanxi, China; 2 Department of Biology,Shaanxi Education College,Xi′an 710061,Shaanxi,China);Studies on antioxidant activities of ethanoic extract from defatted Semen astragali complanati in vitro[J];Journal of Shaanxi Normal University(Natural Science Edition);2008-04
2 OU Li-na ZHANG Jian-jun~(**) ZHANG Yu-jie YAN Xing-li ZENG Feng-ying LI Wei (School of Preclinical Medicine,Beijing University of TCM,Beijing 100029,China);Compare with the content of complanatoside A of commercial Semen Astragali Complanati in different districts[J];Chinese Journal of Pharmaceutical Analysis;2007-05
3 LU Yan-ping1, QIU Feng-zou1,LUO You-di1, CHEN Xue-hong2, CHEN Di-wen3 (1.Shenzhen Longgang District People's Hospital,Shenzhen 518172,China;2.Guangdong Food and Drug Vocational College, Guangzhou 510520,China;3.Guangdong Pharmaceutical College, Guangzhou 510006,China);Optimization of processing technology for Astragalus complanatus by orthogonal experiment[J];China Medical Herald;2008-20
4 Mou Ying,Peng Shaoping,Gu Zhenlun(Department of Pharmacology,Medical School of Soochow University,Soochow University,Shuzhou Institute of Chinese Meteria Medica,Suzhou 215007,China);Study on the Extraction Method of Total Flavonoids of Astragalus complanatus R.Br.by Solid Phase Cartridges[J];Chinese Wild Plant Resources;2006-06
5 Mu Ying,Peng Shaoping,Gu Zhenglun(Suzhou Institute of Chinese Meteria Medica,Department of Pharmacology,Medical School of Suzhou University,Suzhou 215007,China);Determination of Complanatoside in by HPLC with Solid-Phase Extraction[J];Chinese Wild Plant Resources;2009-03
6 HE Cheng, TANG Xiao-jing, CHEN Yu-wu, et al (National Engineering Research Center for R﹠D of TCM Multi-ingredient Drugs, Beijing 100075, China);Determination of Complanatuside in Semen Astragali Complanati and Its Processed Products by HPLC[J];Chinese Journal of Information on Traditional Chinese Medicine;2010-03
7 SUN Jian-zhong1,2, ZHANG Huai1,2, JIA Tian-zhu1,2 , ZHANG Xi3(1. Liaoning University of Traditional Chinese Medicine,Dalian 116600,China; 2. Liaoning Process Engineering and Technology Research Center of Traditional Chinese Medicine,Dalian 116600,China; 3. Weihai Municipal Hospital of Chinese Medicine,Weihai 264200,China);Determination of complanatoside A and rhamnocitrin in Semen Astragali complanati[J];Chinese Traditional Patent Medicine;2010-08
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