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Effect of Phyllanthus emblica L. on Immunity Hepatic Fibrosis in Rats (Ⅰ)

LI Ping1,YANG Zheng-teng2,PENG Bai-cheng2,ZHEN Dan-dan3(1.Guangxi College of TCM,Nanning 530001,China: 2.Nanning Hospital of TCM,Nanning 530012,China;3.The First Hospital,Guangxi College of TCM,Nanning 530012,China)  
Objective:To study the effect of Phyllanthus emblica L.on liver fibrosis indexes in liver fibrosis rats caused by porcine serum.Method:The rats were injected with porcine serum though intraperitonea to lead to the liver fibrosis,and the rats were given the extraction of P.emblica.With the methods of radioimmunity assay,the HA,PⅢNP,LN,SOD,MDA and Hyp were tested at the same time,the TNF-α,TGF-β were also tested.By doing so,the action mechanisms of P.emblica was explored.Result:The extraction of P emblica was able to reduce the content of TNF-α,TGF-β,HA,PⅢNP,LN,MDA and Hyp.It also increased the activity of SOD.The actions were in a dose-dependent manner.Conclusion:P.emblica have a good role in anti-liver fibrosis induced by porcine serum in rats.
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