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《Chinese Journal of Experimental Traditional Medical Formulae》 2010-10
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Effect of Aloe Gel on Agglutination of Wound Surfaces to Second Degree of Scalding Rats

TANG Jian-hong,LIU Chuan-yu ,HE Jie,SU Han (Affiliated hospital ,Guilin University of Medicine,Guilin 541001,China)  
Objective:We have observed the effect of Aloe Gel to the second degree of the scalding rats on the appearing time of epithelium and the healing time and the content of fibronectin in tissue of skin ,it has been proved Aloe Gel has the contribution on promoting the growth of granulation tissue and accelerating the wound to accrete. Method:We had taken the experiment into two groups ,that is the control group ( CG) and the experimental group (EG). We had adopted the immersion method to make rat's naked back the superficial second degree scalding. We had used Aloe Gel to spread on the wound surface of the experimental group with four times per day ,and had used Isotonic Na chloride to handle the wound surface of the control group. Then we had recorded the appearing time of epithelium ,the average healing time and the healing ratio on the 2nd to 24th day. And we also had determined the contents of fibronectin in tissue fluid of the healed skin on the 14th and 24th day after the treatment. Result:To contrast with the control group,we had found the the appearing time of epithelium in the experimental group was earlier,the healing time was shorter obviously,and the healing ratio was higher,the content of fibronectin in tissue of skin had increaed obviously. Conclusion:The polysaccharide and amino acid in Aloe Gel could promote the granulation tissue to growth and contribute the wound to increase healing according to effecting the formation of fibrous tissue in inflammation,the composition and maturation of fibronectin,the contraction and alteration of wounds.
【Fund】: 广西卫生科技计划项目(z2009)
【CateGory Index】: R285.5
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