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《Chinese Journal of Experimental Traditional Medical Formulae》 2015-05
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Phenolic Acids of Lonicerae Japonicae Caulis

JIA Xian-hui;WANG Xiao;ZHANG Yong-qing;Shandong University of Traditional Chinese Medicine;Key Laboratory for Rare Disease of Shandong Province,Institute of Materia Medica,Shandong Academy of Medical Sciences;Shandong Analysis and Test Center;  
Objective: To explore the bioactive components of Lonicerae Japonicae Caulis and to study the phenolic acids of the plant. Method: Compounds were isolated and purified by solvent extraction ethanol extraction,repeated column chromatography on silicagel and Sephadex LH-20. Their structures were elucidated on the basis of physical characteristics and spectral data. Result: Six phenolic compounds were obtained and identified as methyl p-hydroxycinnamate( 1),ethyl caffeate( 2),methyl caffeate( 3),ferulic acid( 4),caffeic acid( 5),and chlorogenic acid( 6). Conclusion: Compounds 1,3 and 4 were isolated from Lonicerae Japonicae Caulis for the first time.
【Fund】: 国家“十二五"科技支撑计划项目(2011BAI06B01)
【CateGory Index】: R284.1
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