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《China Practical Medicine》 2009-15
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Therapeutic effects of mild hypothermia on patients with severe craniocerebral injury

HUANG Hua-dong,HUANG Hai-neng,ZHAO Bang,et al.The Department of Neurosurgery,Affiliated Hospital of Youjiang Medical College for Nationalities,Baise,Guangxi 533000,China  
Objective To investigate the effects of mild hypothermia on the patients after with severe craniocerebral injury.Methods 178 cases with severe craniocerebral injury patients were divided into the mild hypothermic group(89 cases)and the control group(89 cases)randomly.The patients of the mild hypothermic group were treated with mild hypothermia within 24 hours of injury and in control group patients receives the same treatment measures but mild hypothermia was't given.The vital signs intracranial pressure(ICP),blood gas values,blood electrolytes were measured.Results There was no significant in ICP within 24 hours of injury between two groups(P0.05).However,ICP in the mild hypothermic group after 48 hours of injury was significantly lower(P0.01)than the control group.The case fatality and good recovery rate of the mild hypothermic group were 2.25%and 76.40%,but those of the control group were 6.73%and 51.69%,there were significant differences(both,P0.05)between two groups.Conclusion The continuous mild hypothermia treatment is an effective and safe method for patients with severe craniocerebral iniury,which can reduce the mortality and improve the prognosis.
【CateGory Index】: R651.1
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