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《China Practical Medicine》 2019-28
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Clinical study of ginkgo biloba extract injection in the treatment of sudden deafness

ZHANG Jing-yi;GUO Ying-mei;NONG Ying-quan;Foshan Chancheng District Central Hospital;  
Objective To investigate the clinical efficacy of ginkgo biloba extract injection(trade name:Ginaton) in the treatment of sudden deafness. Methods A total of 79 patients with sudden deafness as study subjects were divided into experimental group(40 cases) and control group(39 cases) according to random number table method. The control group was treated with prostaglandil hydrochloride injection, and the experimental group was treated with ginkgo biloba extract injection on the basis of the control group. Observation and comparison were made on clinical treatment effect, hearing loss score and pure tone threshold before and after treatment, grading level of tinnitus and occurrence of adverse reactions after treatment between the two groups. Results The total effective rate of treatment was 97.5% in the experimental group, and that was obviously higher than 82.1% in the control group, and the difference was statistically significant(P0.05). Before treatment, there was no statistically significant difference in hearing loss score and pure tone threshold between the two groups(P0.05). After treatment, the hearing loss score and pure tone threshold in two groups was lower than those before treatment, and the those in the experimental group was significantly lower than those in the control group. Their difference was statistically significant(P0.05). After treatment, the grading level of tinnitus in the experimental group was obviously better than that in the control group, and the difference was statistically significant(P0.05). The incidence of adverse reactions was 2.5% in the experimental group, and that was lower than 15.4% in the control group, and the difference was statistically significant(P0.05). Conclusion Ginkgo biloba extract injection has remarkable effect in the treatment of sudden deafness, and it can effectively improve level of hearing, relieve the symptoms of tinnitus with fewer adverse reactions. It is worthy of application.
【CateGory Index】: R764.437
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Wang ShuYun,et al;Study on the effect of ginaton in treating sudden deafness[J];浙江临床医学;2012-01
【Co-citations】
Chinese Journal Full-text Database 1 Hits
1 GAO Nan;REN Rong;YANG Yintong;Xi'an Fourth Hospital;Hospital of North Western Polytechnical University;;Ginkgo Biloba Extract Treatment of Sudden Deafness Clinical Curative Effect Observation and Prognosis Factors Analysis[J];辽宁中医药大学学报;2015-09
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 TANG Yu ping,LOU Feng chang,WANG Jing hua,LI Yan fang (Department of Natural Pharmaceutical Chemistry,China Pharmaceutical University,Nanjing 210038,China);Studies on the constituentes of flavonoids from Ginkgo biloba leaves[J];中国药学杂志;2001-04
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