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《Chinese Journal of Veterinary Science》 2009-02
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Influence of Zn,Cu to immunity function on Mo poisoned sheep

YANG Zi-jun1,RAN Lin-wu1,WANG Ting1,ZHANG Cai1,WANG Hong-wei1,LIU Feng-jun1,HUANG Ke-he2(1.Livestock Science & Technology College,Henan University of Science and Technology,Luoyang,Henan 471003,China;2.College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China)  
Twenty healthy sheep were divided into five groups of four animals each,fed with different dosage of molybdenum(Mo),copper(Cu) and zinc(Zn)separately:GroupⅠMo 30 mg/(kg·d),GroupⅡMo 30 mg/(kg·d)+Cu 15 mg/(kg·d),GroupⅢMo 30 mg/(kg·d)+Zn 15 mg/(kg·d),GroupⅣMo 30 mg/(kg·d)+Cu 15 mg/(kg·d)+Zn 15 mg/(kg·d),and groupⅤ(control group) sheep drink the deionization water.The experiment last 75 days.The sheep blood samples were collected regularly to determine the percentage of T,B lymphocyte and the α-fibrinoplastin and γ-fibrinoplastin levels.The result showed that in exceed Mo(Mo≥30 mg/(kg·d)) group both the T,B lymphocyte numbers decreased.In Mo(30 mg/(kg·d)) group the α-globulin and γ-globulin serumlevels reduced,Zn(15 mg/(kg·d)) lessen the decrease of γ-globulin,so as Cu(15 mg/(kg·d)) did on α-globulin,and Zn(15 mg/(kg·d))and Cu(15 mg/(kg·d)) has very good synergic effect in protecting from Mo(30 mg/(kg·d)) poisoning.
【Key Words】： sheep Zn Cu molybdenum poisoning immunity function
【Fund】： 河南科技大学博士基金资助项目(09001295)
【CateGory Index】： S858.26
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