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《Chinese Journal of Veterinary Science》 2011-06
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Effect of copper and zinc on the level of molybdenum in liver and kidney of sheep with experimental molybdenum poisoning

YANG Zi-jun,ZHANG Cai,WANG Hong-wei,LIU Feng-jun,RAN Lin-wu,WANG Ji-cang(Livestock Science & Technology College,Henan University of Science and Technology,Luoyang 471003,China)  
Twenty small tail Han sheep were allocated to five groups treated with 30 mg/kg Mo(Ⅰ),15 mg/kg Cu(Ⅱ),15 mg/kg Zn(Ⅲ),30 mg/kg Mo+15 mg/kg Cu+15 mg/kg Zn(Ⅳ) as CuSO4·5H2O or ZnSO4·7H2O,and deionized water(Ⅴ).After 90 days,liver and kidney were collected for detecting the concentration of molybdenum,copper and zinc.Group Ⅰ had higher level of molybdenum in the liver than that of other groups(P0.01),and group Ⅱ and Ⅲ had higher level of Mo in the liver than that of group Ⅳ and Ⅴ(P0.01);group Ⅳ had higher level of copper in liver than that of group Ⅰ,Ⅲ,Vs(P0.01),and higher than group Ⅱs(P0.05);the difference of zinc between each group was obvious in liver(P0.01).Group Ⅰ,Ⅲ had higher level of Mo in kidney than group Ⅱ,Ⅳ,Ⅴ(P0.01),and group Ⅱ was higher than group Ⅳ and Ⅴ(P0.01);Group Ⅰ and Ⅱ had higher level of copper in kidney than group Ⅱ,Ⅲ,Ⅳ's(P0.01);the difference of zinc between each group was obvious in kidney(P0.01).Zinc had an accumulation effect in the liver and kidney,copper had an antagonistic effects on molybdenum in liver.
【Key Words】: molybdenum zinc copper sheep
【Fund】: 国家自然科学基金资助项目(31040081);; 河南科技大学基金资助项目(08ZY017)
【CateGory Index】: S858.26
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