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《Chinese Journal of Veterinary Drug》 2008-02
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Characteristics of the Inclusion Complex of Artemisinin and Its Preventive Effects for Coccidiosis by Eimeria tenella in Chickens

LI Jin-gui,ZHU Kui(College of Veterinary Medicine of Yangzhou University,Yangzhou,Jiangsu 225009;China)  
To expand the usage of artemisinin(Art) in animals,the inclusion complex of artemisinin with β-cyclodextrin(β-CD) was prepared according to the method we had established.The chemical characterization of the inclusion complex of Art with β-CD was identified by XRD and 1HNMR in this study.Both the changes of characteristic peaks in XRD spectrum and the chemicalshift to upfield in 1HNMR comfirmed the formation of the inclusion complex of Art-β-CD.Meanwhile,the preventive effects of the inclusion complex of Art-β-CD on coccidiosis caused by Eimeria tenella in chickens were detected.The results showed that the ACIs were less than 160,which indicated that Art was not a good coccidiostat for chickens.
【CateGory Index】: S858.31
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