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《Chinese Journal of Laboratory Diagnosis》 2019-10
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Infection features of high-risk Human papillomaviruses (HPV) among women in Beijing

WU Li-tao;GUO Nan;LI Baoping;Dongzhimen Hospital,Beijing University of Chinese Medicine;  
Objective To investigate the infection rate and genotype distribution of human papillomavirus(HPV)in Beijing.Methods Retrospective analysis of high-risk HPV genotype from 2183 women who had received treatment in our hospital in 2017.Results There were 407 positive cases of high-risk HPV genotype in all 2183 samples,and the infection rate was 18.61%;there were 15 high-risk HPV genotypes have been detected and the top 5 genotypes were HPV52、51、16、58、39;The infection rate of high-risk HPV decreased at first and then rose as age increases;the infection rate of high-risk HPV of menopause women was higher than that of child-bearing period women;the top 5 genotypes in menopause women were HPV52、51、58、66、56,while HPV52、16、51、58、39 were in child-bearing period women.Conclusion The infection rate of high-risk HPV in Beijing was lower than the reported level of China,and the Genotypic distribution of Beijing was different from that of China;The curve of infection rate of high-risk HPV was Ushape as age increased,so we should pay attention to the women who was≤25 years old and≥65 years old;Compared with menopause women,child-bearing period women had lower infection rate of high-risk HPV but higher risk of cervical cancer.
【CateGory Index】: R711.32;R440
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