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《Chinese Journal of Integrated Traditional and Western Medicine On Gastro-spleen》 2002-04
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Influence on EGG and Peptides of Cholinergic M Receptor Blockaded Rats by Puncturing Acupoints of Stomach Meridian of Foot-yangming

YI Shouxiang,YAN Jie, LIN Yaping ,et al Hunan College of TCM, Changsha 410007  
Objective:To observe the influence on EGG(electrogastrogram) and peptides of cholinergic M receptor blockaded rats by puncturing Zusanli and investigate its external passage and substantial elements.Methods:33 rats were divided into four groups:control group, Zusanli group, Atropine group,Zusanli and Atropine group.Cholinergic M receptor was blockaded by injecting Atropine.The slow wave amplitude variety percentage,slow wave high activity period ratio, number of fast wave cluster of EGG were measured, and contents of MTL,GAS,SP in gastric antrum and plasma were tested by radioimmunoassay.Results: After puncturing Zusanli,the slow wave amplitude variey percentage,slow wave high activity period ratio,number of fast wave clusters of EGG became increased, and the contents of MTL,SP in gastric antrum and plasma were higher. After cholinergic M receptor was blockaded, the above parameters were decreased.The suppressive effect of Atropine on EGG could be partially lightened and the release of MTL and SP were increased by puncturing once again.Conclusion:After vagus cholinergic M receptor was blockaded, the signal of puncturing Zusanli acupoint may regulate gastric activity probably via external SP peptidergic nerve passage.
【Fund】: 国家攀登预选项目 (No.95 -预 - 192 2 1)
【CateGory Index】: R245
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