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《Research of Integrated Traditional Chinese and Western Medicine》 2012-03
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Clinical Observation of Compound Matrine Injection in Treatment of Malignant Ascites by Intraperitoneal Perfusion

ZHANG Liqiang,JIANG Shuming,TIAN Suqing Department of General Surgery,Xinzhou People’s Hospital,Shanxi,Xinzhou 034000,China  
Objective To evaluate the effect of compound matrine injection in treatment of malignant ascites by intraperitoneal infusion.Methods Forty eight patients with malignant ascites were randomly divided into two groups,27 cases in treatment group were griven compound matrine injection combined with cisplatin 1 time a week by intraperitoneal infusion,21 cases in control group were only given cisplatin.After 4 times,the curative effect,patients’quality of life and the level of T cell subsets were evaluated.Results ①There was significant difference between the treatment group and the control group in curative effect,62.96% vs 38.10%(P0.05).②The level of CD3+、CD4+、CD8+and the ratio of CD4+/CD8+ of treatment group increased significantly after treatment(P0.05),and which was higher than that of control group(P0.05).③The PS score of treatment group was lower than that of control group(P0.05).Conclusion Compound matrine injection can mitigate clinical symptoms,improve the patients’quality of life and decrease side effect in treatment of malignant ascites by intraperitoneal infusion.
【CateGory Index】: R730.5
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1 YAO Jian(The First Hospital Affiliated to Harbin Medical University,Harbin 150001);EFFECTS OF COMPOUND SOPHORA INJECTION ON SERUM IL-1β AND TNF-α IN RATS WITH RHEUMATOID ARTHRITIS[J];中国中医药科技;2007-05
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1 Liang Yanran;Jing Xiuna;Lin Danyu;Chen Ying;Bi Wei;Zeng Zhifen;Wu xia;Tao Enxiang;Department of Neurology,Sun Yat-sen Memorial Hospital,Sun Yat-sen University;Department of Neurology,the First Affiliated Hospital of Jinan University;;Effects of rifampicin on caspase-1 activation in rotenone-induced microglia[J];中华脑科疾病与康复杂志(电子版);2015-04
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