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Extraction process of Tongfeng capsule by orthogonal test

LI Yong,HE Wei(Institute of Materia Medica,Guangdong Pharmaceutical University,Guangdong Provincial Key Laboratory of Advanced Drug Delivery,Guangzhou 510006,China)  
Objective: To optimize the extractive process of Tongfeng capsule.Methods: The extractive procedure was studied by orthogonal design with the contents of emodin,chrysophanol,aesculin,aesculetin and the dry extract yield as the index.The extractive time,solvent concentration,solvent amount and extraction frequency were optimized.Results: The extractive process consisted of adding 7-fold of 70% ethanol,decocting 2 times,and 2 h for each time.Conclusion: The optimized extractive technique is stable and efficient with high yields.
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