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《Chinese Journal of New Drugs》 2013-04
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Efficacy of eszopiclone combined with psychotherapy in the treatment of insomnia

PENG Yan1,2(1 Psychological Research Institute of The Chinese Academy of Sciences,Graduate School of Chinese Academy of Science,Beijing 100101,China;2 Department of Psychiatry,Hospital of Guangxi Liuzhou Iron and Steel(Group) Company,Liuzhou 545002,China)  
Objective: To observe the efficacy of eszopiclone combined with psychotherapy in the treatment of insomnia.Methods: Totally 85 patients with insomnia were randomly divided into two groups;43 received eszopiclone combined with psychotherapy and 42 received eszopiclone alone(control) for 8 weeks.Before and after treatment,patients were evaluated by Pittsburgh Sleep Quality Index(PSQI).Results: After treatment,each issue of the PSQI scores decreased significantly in both groups,the time to go to sleep shortened,and the sleeping-time prolonged,the sleep quality and efficiency improved,and the daytime-functions strengthened.There were significant differences between the two groups in the sleep quality,efficiency and PSQI total scores(P0.01).Conclusion: Eszopiclone combined with psychotherapy is significantly more effective in the treatment of insomnia.
【CateGory Index】: R740
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