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Progress in research of preparation technologies and drug-delivery of nanosuspensions

YUAN Hui-ling;YI Jia-ming;ZHANG Cai-yun;LU Chuan-hua;CHEN Wei-dong;Department of Pharmacy,Anhui University of Traditional Chinese Medicine;Anhui Province Key Laboratory of Research and Department of Traditional Chinese Medicine;  
Poorly soluble drugs have seriously limited their widely use in medical field due to low bioavailability. Nanosuspension prepared under mild conditions with fewer side effects has important effects on the increase of the solubility,the dissolution rate and the bioavailability of drugs. In this review,we briefly introduced the preparation technology and the drug-delivery of nanosuspensions. At the same time we discussed the factors influencing the particle size and drug bioavailability,in order to provide references for more researchers.
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