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Application of thermal analysis for drug control

LIN Lan;NING Bao-ming;YANG La-hu;LIU Yi;National Institutes for Food and Drug Control;  
The application,development and prospects of differential scanning calorimetry(DSC)and thermogravimetric analysis(TGA)in the area for drug control currently were introduced in this paper.Based on the work for chemical drug control and chemical reference substance studies,the characterization and prospects of DSC and TGA in pharmaceutical quality analysis,such as melting point,purity and polymorphs,were described.The establishment of database will be an active way to accelerate the application and development of thermal analysis techniques in the field of drug control.Thus,it will be an important and necessary method for the new drug research and drug control.
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