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《Journal of Chinese Medicinal Materials》 2010-02
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Study on Extraction of Anti-diabetes Active Constituents from Potentilla chinesis

ZHAO Chuan, TANG Sheng-an, DUAN Hong-quan(Tianjin Research Center of Basic Medical Science, School of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070,China)  
Objective:To study the extraction technology of anti-diabetes active constituents from Potentilla chinesis. Methods: Through single factor test, the effects of factors such as concentration of ethanol, temperature, ratio of liquid-solid, extraction time and times of extraction were investigated. Through orthogonal experiment, the optimal conditions of extraction were obtained on the basis of single factor test. Results: The optimum extraction conditions of Potentilla flavone from P.chinesis were determined as follows: refluxing for 3 times,1.5 hours each time, and 8-6-6 for the multiple of 60% EtOH and material. Conclusion: The extraction process is stable and suitable for industry.
【Fund】: 国家自然科学基金项目(30772635);; 天津市科委应用基础研究重点基金项目(07JCZDJC05100)
【CateGory Index】: R284.2
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