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《Medical Innovation of China》 2017-26
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Application and Safety Analysis of Pidotimod Therapy for Preventing Infectious Disease of Elderly Patients with COPD

WANG Jian-chang;Wu Zhong-pei Memorial Hospital in Shunde District of Foshan City;  
Objective:To discuss the application and safety of Pidotimod therapy for preventing infectious disease of elderly patients with COPD.Method:From December 2012 to December 2015,100 elderly patients with COPD treated in our hospital were selected and divided into the observation group and the control group according to the random number table method,50 cases in each group.The control group was given regular symptomatic treatment such as keep respiratory tract unobstructed,oxygen uptake,nutrition support,expectorant,spasmolysis,the observation group was given 800 mg Pidotimod on the basis of the control group,both of two groups followed up for 12 months,serum hypersensitive C-reactive protein(hs-CRP) and white blood cell count(WBC),neutrophil counts(NEUT) levels,infectious diseases and adverse reactions occurrence condition of two groups before and after treatment were statistical analyzed.Result:The serum hs-CRP,WBC,NEUT levels of the observation group group after treatment were lower than those of the control group,the difference were statistically significant(P0.05).There were no statistically significant difference between two groups' adverse reaction rates(P0.05).The infectious disease rates after 6 and 12 months treatment of the observation group were lower than those of the control group,the difference was statistically significant(P0.05).Conclusion:Pidotimod treatment can improve inflammation state of elderly patients with COPD,it is conducive to prevent infectious diseases of elderly patients with COPD,which has good security and worth of further clinical promotion.
【CateGory Index】: R563.9
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