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《Study Journal of Traditional Chinese Medicine》 2003-02
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Study of Effect of Shengjiangsan(SJS) on Inhibiting Influenza Virus A in Vivo and in Vitro

睞bstract〕 Aims To prove the antiviral effect and its mechanism of SJS through laboratorial study with modern medical methods, and to offer a scientific foundation for the applying of SJS on influenza. Methods In vitro, influenza virus FM1 were inoculated into MDCK cells, the antiviral effects of SJS were observed. In vivo, the influences of SJS on titer, of influenza virus A in the pulmonary organization was observed in the mice infected with virus from nose. Results In vitro, the minimal effective concentrations of SJS against the influenza virus FM1 was 1.56g/ml, this medicine inhibited the intracellular replication of influenza virus. In vivo, SJS could decrease the virus titer in mouse lung (P0.05). Conclusion SJS inhibited the proliferation of influenza virus A in vivo and in vitro. Based upon the results it appears that the SJS may be valuable in treating Influenza. 〔
【CateGory Index】: R285.5
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