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《Chinese Archives of Traditional Chinese Medicine》 2007-10
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Researches of Polysacchaides from Spores of Agaricusbaizei Murill Inhibiting Transplanted Tumor in the Nude Rats

BAI Ji-qing,XI Xiao-xian,HE Xin-huai(Shaanxi University of TCM,Xianyang 712046,Shaanxi,China)  
Objective:To research the molecular mechanism of polysacchaides from spores of agaricusbaizei murill by observing the function of inhibiting tumor on SGC-7901 in the nude rats.Methods:Human gastric cancer SGC-7901 that grew logarithmically were transplanted subcutaneously to BALB/C-nu/nu mice and model of xenoplanted tumor was established,25 mice were divided randomly into 5 groups,including xianggu polysaccharide group,large,middle,small dose group of polysacchaides from spores of agaricusbaizei murill and blank group.Results:Compared with blank group,large,middle and small dose group of polysacchaides from spores of agaricusbaizei murill and xianggu polysaccharide can inhibit every markedly the growing tumor(P0.01)and can increase the spleen index(P0.05).Conclusion:Polysacchaides from spores of agaricusbaizei murill can inhibite tumor by raising function of immunity of body.
【Fund】: 陕西省教育厅科研计划项目(01JK105)
【CateGory Index】: R285.5
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