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《Chinese Archives of Traditional Chinese Medicine》 2008-08
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Clinical Observation of Berberine in Treatment of Non-Gonococcal Urethritis and Cervicitis Due to Chlamydia Trachomatis

LI Jin1,LIN Yi1,WU Ying-ling2,WANG Pei-tu3(1.Department of Dermatology,Shenzhen East Lake Hospital,Shenzhen 518020,Guangdong,China;2.Shenzhen Hospital for Women and Children,Shenzhen 518020,Guangdong,China;3.General Hospital of Armed Police Force,Shenzhen 518020,Guangdong,China)  
Objective:To observation the efficacy and safety of berberine in treating non-gonococcal urethritis and cervicitis due to chlamydia trachomatis.Methods:86 patients with non-gonococcal urethritis and cervicitis were randomized into treatment Group(n=44)and control Group(n=42).Treatment group was treated oral berberine 0.4g,tid for 14 days.Control group was treated oral doxycycline 0.1g,bid for 14 days.The efficacy and safety of all patients were observed before and after the treatment.Results:The overall efficacy rates of berberine and doxycycline were 65.9% and 73.8%,Bacteria elimination rates were 65.9% and 73.8%,and the side effect rates wore 18.2% and 14.3% respectively.No significant differences were observed between the two groups.Conclusion:Berberine is effective and safe in treating non-gonococcal urethritis and cervicitis due to chlamydia trachomatis.
【Fund】: 深圳市科技信息局资助项目(200703143)
【CateGory Index】: R275.9
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