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《Chinese Archives of Traditional Chinese Medicine》 2009-03
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The Changes of ET and NO Contents in Gastric Mucosa Induced by Hemorrhagic-Shock Reperfusione and The Effects of DanShen Extract F.

YAO Chang-bai1,ZHANG Li-hong2,ZHAO Guang-yi2(1.The Affiliated Hospital of Liaoning University of TCM,Shenyang 110032,Liaoning,China;2.The Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning,China)  
Objective:to study the relation between the protective effects of DanShen Extract F(DSEF)on gastric mucosa injury due to Hemorrhagic-Shock reperfusion and the content of endothelin(ET)and nitric oxide(NO)in gastric mucosa.Methods:rats were randomly divided into four groups:group SC(rats undergoing all procedures but hemorrhagic shock);group HE(rats suffered from hemorrhagic shock for 20 min),group NS and DSEF(rats received blood reperfusion after shock for 20min and were killed after 20min).Rats in group DSEF received intravenous infusion of DSEF,and normal saline was infused(0.03mL/min)in the other groups.Result:(1)blood lossing and MAP were similar among group HE,NS,DSEF(P0.05),and there was no marked difference of MAP between before shock and after reperfusion(P0.05).(2)The index of injury in group DSEF was markedly lower than that in group NS(P0.01),and the index in group HE was 0.(3)As compared with those in group SC,the level of NO decreased significantly,but the content of ET increased markedly in group NS(P0.01).In comparsion with those in group NS,the level of NO rose obviously,while the content of ET reduced dramatically in group DSEF(P0.01).Conclusion:the gastric mucosal lesion caused by the reperfusion may be in close contact with the decreasing of NO and the increasing of ET in gastric mucosa and DSEF can inhibit the changes to protect gastric mucosa from reperfusion impairment.
【Fund】: 辽宁省自然科学基金资助项目(2003159)
【CateGory Index】: R285.5
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【References】
Chinese Journal Full-text Database 1 Hits
1 GAO Ying1,YANG Ji-wu2(1.Graduate School,Liaoning University of Traditional Chinese Medicine,Shenyang,110032,Liaoning,China; 2.The First Hospital Affiliated to Liaoning University of Traditional Chinese Medicine,Shenyang,110032,Liaoning,China);Clinical Observation of Kang Xiu Ning Decoction Combined with Western Medicine with Cardiogenic Shock of 30 Cases[J];Liaoning Journal of Traditional Chinese Medicine;2011-05
【Citations】
Chinese Journal Full-text Database 3 Hits
1 Liu Jinsong, Hou Xiaohua△ Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022;Protective Effect of Nitric Oxide on Gastric Mucosa[J];Acta Universitatis Medictnae Tangji;2004-05
2 ZHANG Lihong, ZHANG Jin, YAO Changbai, et al. Department of Anesthesiology, Second Clinical College, China Medical University, Shengyang 110003;Comparison of effects of Dan Shen Extract F and cimetidine on reperfusion injury in gastric antrum[J];Chinese Journal of Anesthesiology;2000-07
3 YAO Changbai, ZHANG Lihong, LI Hequan Department of Surgery, Liaoning Provincial People's Hospital, Shenyang (110015);Mucosal Injury of Gastric Corpus by Hemorrhage Reperfusion and Comparison between Preventing and Therapeutic Effect of Salvia Extract F and Cimetidine[J];CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN MEDICINE;2000-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Huang Shi Lin Shouning He Shanming,et alRuikang Affiliated Hospital of Guangxi Traditional Chinese Medical University,Nanning,530011;Clinical Observation on Anwei Decoction in Treatment of Peptic Ulcer[J];Guangxi Journal of Traditional Chinese Medicine;2007-03
2 Zhou Lan,Sun Guihua, Song Hong Department of Gastroenterology of Guangzhou General Hospital of Guangzhou Military District 510010;Preservation of yangweisan on mucosa of the wister's stomach caused by Indometacin[J];Guangzhou Medical Journal;2001-06
3 TANG Jing,ZHU Jing-ci(Department of Nursing,Third Military Medical University,Chongqing 400038,China);Influence of Econutrition on Gastric Mucosal Blood Flow and Gastric Mucosal NO in Rats with Severe Brain Injury[J];Nursing Journal of Chinese People's Liberation Army;2007-09
4 LI Xiao-fang *,ZHANG Pei-rong *Department of Emergency,the People's Hospital of Henan Province,Zhengzhou 450003,China;Plasma endothelin level in patients with acute gastric mucosal injury[J];Clinical Focus;2003-11
5 Zhao Guangyi,Gao Linlin,Meng Lingxin.Department of Anesthesia,Second Affiliated Hospital,China Medical University,Shenyang 110004 CHINA;Effects of transection of the cervical sympathetic trunk on gastric mucosal blood flow and the changes of NO in water immersion restrain rats[J];The Journal of Clinical Anaesthesiology;2005-11
6 Song Yu-lin, Xie Hui-zhun, Liang Wei-long, et al Department of Endoscope, the First Afflieated Hospital of Anhul Medical University;Relationship Between Endothelit - 1 in the Gastrointestinal Mucosa and Peptic Ulcer[J];Chinese Journal of Clinical Gastroenterology;1999-03
7 Qin Dalian, et al Department of Pharmacology, Luzhou Medical College[WT5HZ];INHIBITION EFFECTS OF SI KANG SHEN NONG YANG SHENG PIAN TABLET ON EXPERIMENTAL GASTRIC ULCERS[J];Journal of Luzhou Medical College;2001-01
8 BAI Jianle,LIU Jianping,ZHANG Shujin. Department of Endocrinology,Shijiazhuang Hospital of Traditional Chinese Medicine,Hebei Province,Shijiazhuang 050011;Study of traditional Chinese medicine for the activating blood and dispearing stasis on gastric mucosal blood flow of rat with acetic acid-induced gastric ulcer[J];Hebei Journal of Traditional Chinese Medicine;2011-07
9 LOU Haiou, TANG Yong, PU Yi, et a/. f Xinqiao Hospital of the Third Military University of Medical Science, Chongqing 400037, China);The Influence of Various Pairing of Acupoint on Plasma En- dothelion of Patients Suffering from Peptic Ulcer[J];New Journal of Traditional Chinese Medicine;2003-05
10 Feng Yanchang,Liu Zhimin,Yang Weijian,et al;Changes of plasma endothelin in patients with portal hypertension pre-and-post splenectomy[J];Shandong Medical Journal;2002-03
【Co-references】
Chinese Journal Full-text Database 7 Hits
1 Wang Jianshe1,Li Kaili,Dong Dacui2,Zhu Qingsheng1,Li Lijun1,Wang Xia2,Zhang Yan2(1.Department of Anatomy,Conghua Medical College,Guangzhou 510925;2. Department of Anatomy,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China);Expression of NOS and neuron apoptosis in the cerebral cortex after brain ischemia reperfusion injury in rat and protective effects of salvia miltiorrhiza[J];Chinese Journal of Anatomy;2009-02
2 SONG Xiaoyuan,MA Ping (The Second Clinical Medical College of Shanxi Medical University,Taiyuan 030001,Shanxi,China);Effects and Its Mechanisms of Limbs Ischemia-Reperfusion in Rats on the Cell Apoptosis of Spinal Cord Neurons[J];Journal of Shanxi Medical College for Continuing Education;2009-02
3 LI Hao,LIU Kai-xiang,FENG Jun-lin (The Affiliated Hospital of Guilin Medical College,Guilin 541002,China);Effect of Tanshinone ⅡA on Content of NO and Activities of NOS and iNOS in Cerebral Ischemic Reperfusion Injury Rats[J];Chinese Journal of Information on Traditional Chinese Medicine;2009-01
4 GAO Dan, KONG Xiao-yan, DONG Shu-yun, LI Hong-jie, ZHAO Li-jun, MEN Xiu-li, ZHOU Hong-xia, ZHANG Lian-yuan(Department of Pathophysiology, North China Coal Medical College, Tangshan 063000, China. );Effect of nitric oxide on apoptosis in lung injury following ischemia-reperfusion of hind limbs[J];Chinese Journal of Pathophysiology;2007-11
5 ;一氧化氮在大鼠肢体缺血/再灌注后肾组织细胞凋亡中的意义[J];Chinese Journal of Applied Physiology;2009-02
6 CHEN Guang-bin1,CHEN Hua-ping1,WU Tie2,LIN Jian-tao2,CUI Liao3(1.Department of Pharmacy,the Affiliated Hospital of Guangdong Medical College,Guangdong Zhanjiang 524001,China;2.Institute of Chinese Materia Medica,Guangdong Medical College,Guangdong Zhanjiang 524023,China;3.Guangdong Key Laboratory for Research and Development of Natural Drugs,Guangdong Zhanjiang 524023,China);Effect of Danshensu on the iNOS、NOS and NO level in neonatal rats with hypoxic-ischemic brain injury[J];Chinese Journal of Hospital Pharmacy;2008-16
7 LIU Jie1,HE Xiao-min2,TAN Min-yi2,CHEN Jian-wen3(1.The Third Affiliated Hospital,Sun Yat-sen University,Guangzhou 510630,Guangdong,China;2.The First Affiliated Hospital,Guangdong,Sun Yat-sen Universty,Guangzhou 510080,Guangdong,China;3.School of Pharmaceutical Science,Sun Yat-sen Universty,Guangzhou 510080,Guangdong,China);Effects of SMI on Hemodynamics in Shock Rats and its Mechanisms[J];Chinese Archives of Traditional Chinese Medicine;2009-11
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 HOU Xiao-Hua (Dept of Gastrorterology,Union Hospital, Tongji Medical University,Wuhan 430022);The effect of colloidal bismuth subcitrate on the gastric blood flow in rats with ethanol-induced gastric ulceration[J];Chinese Pharmacological Bulletin;1993-05
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