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《Chinese Archives of Traditional Chinese Medicine》 2012-01
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Optimisation for Flavonoids Extraction from Mosla chinensis Maxim.By Response Surface Method

ZAHNG Qi1,2,HAO Yun-yun1,YU Chen-huan1,WU Qiao-feng1(1.Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang,China; 2.Zhejiang Chinese Medical Hospital,Hangzhou 310018,Zhejiang,China)  
Objective:To optimize the extraction conditions of flavonoids from Mosla chinensis Maxim.Method:Solvent quantity,extraction time and times of extraction as investigation factors had been raised to extract the total flavonoids determined by the method of spectrophotometry.The procedure for the extraction was performed with the extraction yield of total flavonoids as the response.Response surface method(RSM) was applied to determine the optimum extraction process.Result:The optimum extraction condition was as follows: concentration of alcohol was 60%,extraction 1 time,2.2 hours each time,ratio of liquid to solid 33 at 90℃.The extraction rate of flavonoids under this condition was 37.85 mg/g.Conclution:The method to extract flavonoids from Mosla chinensis Maxim is simple and feasible.It can provide the scientific basis for further development of Mosla chinensis Maxim.
【Fund】: 浙江省自然科学基金资助项目(Y2080313);; 浙江省新苗人才计划资助项目(2010R410055)
【CateGory Index】: R284.1
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