Effects of cadmium on Serum FSH and LH levels in female rats
YAN Ping LI Huangyuan ZHANG Wenchang ( Public Hygiene Department of Tujian Medical University, 350004)
[Objective] To study Effects of cadmium on Serum FSH or LH levels in Female rats. [Methods]Female SD Rats were given cadmium subactuely and subchronicly with vary doses (respectively 010.25(or 0.5) 、1.0 mg/kg·d) .one part of rats were given cadmium for 7 days and for 14 days, then serum follicle - stimulating - hormone (FSH) luteinizing hormone (LH) in rat were measured. The other part of rats were given cadmium for 30 days and serum FSH or LH in rat were measured. [Results] Serum FSH or LH was not significant different in group given cadmium of low or high dose for 7 days and for 14 days compared with that of control group ( P 0.05) . there was still no difference of serum FSH or LH level among each group given cadmium for 30 days ( P 0.05) . [Conclusion] Under this condition,it is concluded that there was not significant change of serum FSH or LH level in female rat given cadmium. It is suggested that function of Pituitary in female rats was still not adversed or maintain the normal range of FSH or LH through blance function of Pituitary when function of Pituitary in female rats was adversed under the condition of expose to cadmium subactuely and subchronicly.
【CateGory Index】： R114