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《Journal of Emergency in Traditional Chinese Medicine》 2019-01
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Study on the Efficacy and Safety of Huangqi Chongteng Decoction on Ischemic Stroke Patients with Qi Deficiency and Blood Stasis

He Haixia;She Yan;Liu Fang;The First Affiliated Hospital of Hunan TCM University;  
Objective: To investigate the effect of Huangqi Chongteng Decoction on the inflammatory factors and neurological function in patients with ischemic stroke of Qi deficiency and blood stasis type. Methods: 88 patients were randomly divided into control group and observation group. The control group was treated with routine Western medicine. The observation group was treated with Huangqi Chongteng Decoction on that basis. The efficacy,inflammatory factors,neurological function,hemorheological parameters and adverse reactions were compared. Results: The effective rate in the observation group was 90.91%,higher than that in the control group(75.00%)(P 0.05). Before treatment,there were no significant differences in TNF-α,IL-6,hs-CRP,neurological deficit scores,high-shear and low-shear whole blood viscosity,hematocrit and fibrinogen levels between the two groups(P 0.05). After treatment,data above were significantly decreased(P 0.05),and compared with the control group,the decrease in the observation group was more obvious(P 0.05). No significant adverse reactions occurred in both groups during the treatment. Conclusion: The effect of Huangqi Chongteng Decoction combined with Western medicine is more significant than that of Western medicine alone on patients with ischemic stroke of Qi deficiency and blood stasis type. Its mechanism may be related to reducing the level of inflammatory factors,improving nerve function and reducing hemorheological indexes.
【Fund】: 湖南省教育厅科研项目(15C1034)
【CateGory Index】: R277.7
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