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Content of Levocarnitine determined by HPLC

Gao Yianxia, Li Junde , Zhang Jing, Chen Yujie (Hebei Province Institute of Drug Control, Shijiazhuang 050011 , P.R.China) (Shijia zhuang Pharmacentical co. (group))  
Objectives: To determine the content of levocarnitine by HPLC. Method: Spherisorb C18 colunm was used, menthanol (0.05 mol- L-1)-potassium dihydrogen phosphate(pH = 2. 4) (35: 65) were served as mobile phase, it was detected at wavelength 225 run with UV-detector. Result: Levocamitine concentration presented a good linear relation within a range of 0.1-0. 8 mg-ml-1. The average recovery was 99.8 % . Conclusion: This method is rapid, simple, and accurate.
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