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《China Pharmacist》 2008-09
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Study of Lactobacillinn on Eradication the Helicobacter Pylori Infection

Liang Zhigen Quan Huabin Yu Aixing Huang Liyan(Department of Internal Medicine,People's Hospital of Zhongshan city,Guangdong,Zhongshan 528403,China)  
Objective:To study the efficacy of Lacidophilin on eradication the Helicobacter priori(Hp) infection.Method:The ~(14) C-urea breath test(14C-UBT) and rapid urease test(RUT) were examined by gastroscopy with Hp positive outcome in 66 patients with peptic ulcer,chronic cerosive gastriitis and atrophic gastritis were randomly divided into two groups.Thirty-six patients in test group were treated by Lacidophilin,Rabeprazole Amoxicillin and Clarithromycin ;Thirty patients in control group were treated by Rabeprazole, Amoxicillin,and Clarithromycin.The course of treatment was 7 days.Result:After 4 weeks,Hp was examined by ~(14)C-UBT and RUT. Hp were 31 subjects eradicated in the test group and 19 cases eradicated in the control group.The eradication rate(86.1%) of test group was higher than that (63.3%) of control group (P0.05).The side-effect was 2 patients (5.5%) in test group,I0 patients (33.3%) in control group (P0.01).Conclusion:Lacidophilin,Rabeprasole,Amoxicillin and Clarithromycin on eradicate Hp is better than that Rabeprazole,Amoxicillin and Clarithromycin triple therapy.
【CateGory Index】: R573
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