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《Chinese Journal of Medical Imaging Technology》 2004-02
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CT perfusion in patients with lung neoplasms

ZHAO Zhen-jun,LIANG Chang-hong,XIE Shu-fei,HE Hui,RU Guang-teng (Department of Radiology,the Guangdong Provincial People's Hospital,Guangzhou 510080,China)  
Objective To evaluate the significance of CT perfusion in 46 patients with lung neoplasms.Methods A prospective study was undertaken in patients with pulmonary nodules using cine dynamic scan of MSCT. They were histologically proven as peripheral lung cancer in 23 cases,central lung cancer in 6 cases,tubercle in 7 cases,lung abscess in 3 cases,unspecific inflammation in 3 cases,inflammatory pseudotumor in 1 case,aspergilloma in 1 case and hamartoma in 2 cases. The diameter of lesions was 2-7 cm (mean 4 cm) for malignancy and 2-5 cm (mean 3 cm) for benignancy. Using 8-row detector spiral CT,cine scan was performed with 5 mm slice thick /4 slices,1 second scan time per circle,40 s acquisition time and 120 kV,80 mA. Total 50 ml contrast medium (300 mgI/ml) was administered at a delay 5.6 s and a rate of 4 ml/s from forearm superficial vein with hyperbaric injector. The CT data were transferred to a workstation and analyzed with a CT perfusion 2-body tumor software. The parameters of CT perfusion include blood flow (BF),blood volume (BV),mean transit time (MTT) and permeability surface (PS).Results In patients with lung cancer,BF,BV,MTT and PS of the lesions were (38.7±31.9) ml/(min·100 g),(10.1±4.2) ml/100 g,(21.8±10.8) s and (47.3±22.3) ml/(min·100 g).When BV≥6 ml/100g was set as a diagnostic threshold,the sensitivity,specificity,positive predict values and negative predict values were 100%,64.7%,82.9% and 100% respectively. When PS≥30 ml/(min·100g) was set as a diagnostic threshold,the sensitivity,specificity,positive predict values and negative predict values were 86.2%,88.2%,92.6% and 79% respectively.Conclusion BV and PS measured by CT perfusion might be as parameters of diagnosis of lung cancer.
【CateGory Index】: R734.2
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Chinese Journal Full-text Database 10 Hits
1 LIANG Kunru,KANG Jianghe,DUAN Shaoyin,et al.Department of Radiology,Zhongshan Hospital of Xiamen University,Xiamen,Fujian Province 361004,P.R.China;The Study of 64-slice VCT Perfusion in Pulmonary Mass[J];Journal of Clinical Radiology;2009-04
2 WANG Shu-xia, TANG An-wu, LIU Hui(Guangdong Provincial People's Hospital, Guangzhou 510080, China);FDG-PET and CT features in pulmonary inflammatory pseudotumor[J];Journal of China Clinic Medical Imaging;2006-01
3 GE Ying, WU Jian-lin (Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian Liaoning 116011, China);Research status of MSCT perfusion in pulmonary diseases[J];Journal of China Clinic Medical Imaging;2007-09
4 SHAO Yan-hui,QIAN Nong,XUE Yue-jun,DAI Yi-hong (Department of Radiology,Changzhou Second Hospital Affiliated of NJMU,Changzhou 213003,China);Elementary investigation of chronic obstructive pulmonary disease with multi-slice CT per-fusion imaging[J];Acta Universitatis Medicinalis Nanjing(Natural Science);2007-07
5 YANG Li-li,ZHANG Zhi-yuan.(The Affiliated Hosp.of Ningxia Med.Coll.,Yinchuan 750004,China);The research of pulmonary masses with different-phase dynamic enhanced multi-slice CT[J];Ningxia Medical Journal;2008-04
6 GE Ying,LI Zhi-yong,WU Jian-lin(Department of Radiology,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China);CT perfusion in prognosis and evaluation of therapeutic effect of radiation therapy and chemotherapy of lung carcinoma[J];Chinese Journal of Interventional Imaging and Therapy;2009-05
7 LI Shu-ping,ZHU Hai-yun,TIAN Jian-ming,WANG Min-jie,CHEN Wei,SHI Li-jing,LI Yan-ling,SHAO Cheng-wei,WANG Jin-chun(Department of Radiology,PLA 455 Hospital,Shanghai 200052,China);Preliminary Research of MSCT Perfusion Imaging in Normal Pulmonary Parenchyma with Breath-hold[J];Journal of Practical Radiology;2008-04
8 ZHANG Xiao-jun,ZHOU Huai-qi,WANG Gang,GUO Ji-gang,XU Feng(Department of Radiology,the First Hospital of Lanzhou University,Lanzhou 730000,China);The Value of 64-slice Spiral CT Perfusion Imaging in Solitary Pulmonary Nodule[J];Journal of Practical Radiology;2008-06
9 ZHOU Mo-ling, LIU Jin-kang, XIONG Zeng, ZHU Zhi-ming,CHEN Wei (Department of Radiology, Xiangya Hospital of Central South University,Changsha 410008,China);The Application of Multi-slice CT Perfusion Imaging in Diagnosing Pulmonary Neoplasms[J];Journal of Practical Radiology;2008-09
10 YAN Qiao-huan,LV Ying-gang,DAI Li-juan.The First Hospital of Handan,Handan 056002,China;Volue of Multi-slice Spiral CT Perfusion Imaging for Peripheral Lung Cancer[J];Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease;2009-01
Chinese Journal Full-text Database 2 Hits
1 LIU Xiang,DAI Jian ping ( Department of Neuroradiology,Beijing Neurosurgical Institute,Beijing 100050,China);Comparison Study of Different Perfusion Parameter Maps in the Evaluation of Cerebral Ischemic Lesions[J];Chinese Journal of Medical Imaging Technology;2003-02
2 QIAN Yin feng, YU Yong qiang, ZHEN Fei qun, et al (Department of Radiology, the First Hospital, Anhui Medical University, Hefei 230022, China);Primary Extra- and Intra-axial Brain Tumors: Differentiation by Using Perfusion MR Imaging[J];Chinese Journal of Medical Imaging Technology;2003-06
Chinese Journal Full-text Database 9 Hits
1 XU Jianfeng SHI Yuxin (Department of Radiology,Affiliated Hospital of Nantong Unviersity,Nantong 226001,China);Brain Metastasis and Meningomas:Differentiation by Perfusion CT Imaging[J];Clinical Medical Journal of China;2005-05
2 ZHONG De-xiong1,MA Yun-biao1,FAN Shu-yu1,QIU Jianyi1,LIU Yi-min2,ZHU Zi-feng1 (1.Department of Radiology,Huangqi Hospital of Nanhai District in Foshan City,Nanhai,Guangdong 528248,China;2.Department of Neurology,Huangqi Hospital of Nanhai District in Foshan City,Nanhai,Guangdong 528248,China);Dynamic CT scanning for ultra-acute phase brain infarction[J];Journal of Youjiang Medical College for Nationalities;2008-02
3 CAO Li-rong.(Department of Imaging,The Fourth Central Hospital of Tianjin,Tianjin 300140,China);CT Perfusion Imaging in Prophase of Ischemic Cerebrovascular Disease[J];Medical Recapitulate;2007-08
4 WEI Xin-hua, LONG Li-ling, HUANG Zhong-kui,LI Wen-mei, YE Wei (Department of Radiology,the Central Hospital of Hengyang,Hengyang421001, China);Perfusion-weighted MR imaging in preoperative assessment of histological grade of astrocytoma[J];Chinese Journal of Medical Imaging Technology;2004-03
5 BAI Rong-jie, HAN Ming-jun, WANG Li-ping, HAN Xue, WEI Qing-tang (Department of Radiology, the First Affiliated Hospital of China Medical University, Shenyang110001, China);CT perfusion imaging in solitary pulmonary nodule[J];Chinese Journal of Medical Imaging Technology;2004-06
6 CHEN Wei wei, QI Jian pin *, XIAO Ming, SONG Jin mei (Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China);Consistency between two methods for penumbra assessment by CT perfusion in hyperacute cerebral ischemia[J];Chinese Journal of Medical Imaging Technology;2005-02
7 GAO Yang, NIU Guang-ming~*, HAN Xiao-dong, GUO Dong-ling, ZHANG Ying(Department of MR,First Affiliated Hospital, Inner Mongolia Medical College, Huhhot 010050, China);Combined application of MR imaging technique in astrocytoma[J];Chinese Journal of Medical Imaging Technology;2005-03
8 SHI Rui-hua,ZHAI Ren-you,QIAN Xiao-jun,LU Wan-hong,GU Hua(Department of Radiology,Chaoyang Hospital,Capital Medical University,Beijing 100020,China);MR perfusion weighted imaging in evaluation of benign and malignant meningiomas[J];Chinese Journal of Medical Imaging Technology;2010-02
9 LIU Shi-li,LENG Jing,SUN Hua-san.(Department of Neurology,Jilin Chemical Corporation Hospital,Jilin 132021,China);CT perfusion imaging in acute ischemic stroke rt-PA thrombolysis[J];Journal of Apoplexy and Nervous Diseases;2011-02
Chinese Journal Full-text Database 10 Hits
1 Liao Meiyan, Sun Junmo, Zhang Zaipeng, et al Department of Radiology, Zhongnan Hospital, Wuhan University, Wuhan 430071,China;Spiral CT Diagnostic Value in Assessing Growth and Malignancy Status of Pulmonary Nodule[J];Journal of Hubei Medical University;2003-04
2 Wu Kaisong, Liu Mingqiu, Xu Qiyong, et al Department of Respiratory, Zhongnan Hospital, Wuhan University, Wuhan 430071, China;Study on Relationship Between P53 and Vascular Endothelial Factor Expression and Microvessel Density in Non-small Cell Lung Cancer[J];Journal of Hubei Medical University;2004-06
3 LIU Chuntang.Department of CT,Shijiazhuang First Hospital,Shijiazhuang 050011;The relationship between microvessel density and MSCT perfusion in lung mass[J];Hebei Medical Journal;2006-07
4 PENG Xiu-bin * , LUO Yun-hui,DU Zhong-li,HUANG Shi-kui,HE Jing (Department of Radiology, Third Affiliated Hospital of Jinan University, Zhuhai 519000, China);CT appearance and p16 gene abnormality of peripheral lung cancer[J];;2005-02
5 WU Yiming, LI Weimin,LI Zhuowei,WANG Xinchao,MA Yuying,XU Yubao,CHEN Chen Department of occupational Health and Health Toxicology, Henan Medical University, Zhengzhou 450052;Establishment and significance of animal model about occurring and developing in rats lung carcinoma[J];JOURNA OF HENAN MEDICAL UNIVERSITY;2000-03
6 Luo Suqiong;Liu Xueze;Wang Chaojun (1.Research Unit of Pneumoconiosis,School of Public Health; 2.Institute Of Cancer Research);Co-carcinogenic Effcct of Crocidolite Plus Benzo(a)pyrene on the Lungs of Rats[J];JOURNAL OF WEST CHINA UNIVERSITY OF MEDICAL SCIENCES;1995-02
7 CHEN Long bang 1, LI Gui yuan 1, WANG Jing hua 1, ZHOU Xiao jun 2, MA Heng hui 2, XU Wei 2 (1.Department of Oncology; 2. Department of Pathology, Nanjing General Hospital of Nanjing Command, Nanjing 210002,Jiangsu, China);Expressions of VEGF and MMP-2 in human non-small cell lung cancer and the relationships between VEGF and MMP-2 and tumor angiogenesis[J];Bulletin of Medical Postgraduate;2002-06
8 ZHOU Quan, CHEN Jin-cheng, CHEN Yong-mei (Dept. of Medical Imaging, First Affiliated Hospital of JNUMC, Guangzhou 510630, China) [;CT appearances of lung cancer(An analysis of 94 cases)[J];Journal of Jinan University(Natural Science & Medicine Edition);2000-04
9 XIAO Xiang-sheng,DONG Sheng,DONG Wei-hua,ZHANG Dian-bo,LI Xiang-sheng,SHI Jing-yun. Department of Radiology,Chang Zheng Hospital,The Second Military Medical University,Shanghai 200003,China;Serial research of blood supply for lung cancer[J];Journal of Interventional Radiology;2008-03
10 Feng Xiaoan Dept.Ultrasound,Tsinghua University Hospital,Beijing 100084,China;Diagnostic Value of Ultrasonography in Differentiation between Thyroid Adenoma and Solitary Nodular Goiter[J];Journal of Clinical Ultrasavnd In Medicine;2002-02
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 JI Hong-jian, CHEN Li-ping, WANG Hui,CHEN Yong-de. Department of Respiratory Diseases, No. 85 Hospital of PLA, Shanghai 200052, China;Non-vascular interventional therapy for respiratory diseases[J];Journal of Interventional Radiology;2009-01
2 YANG Jie,YANG Ya-ying,HAN Dan (Dept. of CT,The 1st Hospital Affiliated to Kunming Medical University,Kunming Yunnan 650032,Chian);Advancement of CT Perfusion and MRI Perfusion Imaging Research to Cervical Lymph Node Lesions[J];Journal of Kunming Medical University;2008-S1
3 YANG Zhiyun,MENG Quanfei,XU Qiaolan,et al.Department of Radiology,the Affiliated Hospital of Sun YetSen University,Guangzhou,Guangdong Province 510080,P.R.China;CT Perfusion Imaging of Cervical Lymph Nodes[J];Journal of Clinical Radiology;2007-09
4 JIN Zhifa,LUO Liangping,CHEN Jincheng,et al.Department of Radiology,Jiangmen Affiliated Hospital of Sun Yat-sen University,Jiangmen,Guangdong Province 529030,P.R.China;The Study of Combination of CT Perfusion and Dynamic Contrast-enhanced CT in the Differential Diagnosis of Pulmonary Nodule or Mass[J];Journal of Clinical Radiology;2008-05
5 BAI Rongjie,CHENG Xiaoguang,SHEN Baozhong,et al.Department of Radiology,Beijing Jishuitan Hospital,Beijing 100035,P.R.China;Evaluation of Microvessel Structure of Solitary Pulmonary Nodules with 64-slice Spiral CT Perfusion Imaging[J];Journal of Clinical Radiology;2008-08
6 LIANG Kunru,KANG Jianghe,DUAN Shaoyin,et al.Department of Radiology,Zhongshan Hospital of Xiamen University,Xiamen,Fujian Province 361004,P.R.China;The Study of 64-slice VCT Perfusion in Pulmonary Mass[J];Journal of Clinical Radiology;2009-04
7 ZHANG Xiaobo,DENG Dong,LONG Liling,et al.Department of Radiology,the First Affiliated Hospital of Guangxi Medical University,Nanning,Guangxi Zhuang Autonomous Region 530021,P.R.China;The Correlation of 16-Slice Spiral CT Perfusion Imaging with Angiogenesis in Solitary Pulmonary Lesion[J];Journal of Clinical Radiology;2009-06
8 LU Na, GUO Qi-yong, REN Ying, BI Chun-long, CHEN Li-ying (Department of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China);Perfusion imaging with 64-slice CT in diagnosis of pancreatic cancer[J];Journal of China Clinic Medical Imaging;2007-08
9 GE Ying, WU Jian-lin (Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian Liaoning 116011, China);Research status of MSCT perfusion in pulmonary diseases[J];Journal of China Clinic Medical Imaging;2007-09
10 XU Qiu-zhen1,TENG Gao-jun1,CHU Cheng-feng1,DENG Gang1,ZHU Xiao-li2,YANG Ming1,WU Min1(1.Department of Radiology,Zhongda Hospital,Southeast University,Nanjing 210009,China;2.Department of Respiratory,Zhongda Hospital,Southeast University,Nanjing 210009,China);Prelimary application of perfusion imaging in body tumor with 64-slice CT[J];Journal of Southeast University(Medical Science Edition);2007-06
China Proceedings of conference Full-text Database 1 Hits
1 Zhao-xiang YE,Jian-yu XIAO,Xin-peng ZHANG Key Laboratory of Cancer Prevention and Therapy,Department of Radiology,Tianjin Medical University Cancer Institute & Hospital, Tianjin 300060,China;Diagnostic value of CT perfusion for evaluating cervical lymph nodes[A];[C];2009
【Secondary Citations】
Chinese Journal Full-text Database 6 Hits
1 Yu Yongqiang,Zheng Feiqun,Bo Ya,et alDepartment of Radiology,First Hospital of Anhui Medical University,Anhui 230022;Correlative Study of Perfusion MR Imaging with Pathologic Grade in Gliomas[J];Chinese Journal of Medical Computed Imaging;2001-03
2 QIAN Yinfeng, YU Yongqiang, CHEN Jun, ZHENG Feiqun, ZHANG Cheng, BAI Ya, LI Xuan, WU Jinmin. Department of Radiology, The First Hospital, Anhui Medical University, Hefei 230022, China;Evaluation of tumor vessel permeability in astrocytomas with MR perfusion weighted imaging (PWI)[J];Chinese Journal of Radiology;2002-08
3 LIU Xiang, DAI Jianping, SUN Bo, et al Department of Neuroradiology, Beijing Neurosurgical Institute, Beijing 100050;The preliminary research of CT perfusion imaging in intraaxial ischemic disease[J];CHINESE JOURNAL OF RADIOLOGY;1999-07
4 HAN Hongbin, XIE Jingxia. The Third Hospital of Beijing Medical University,Beijing 100083;The study of MR Susceptibilitycontrast cerebral perfusion imaging[J];CHINESE JOURNAL OF RADIOLOGY;1999-07
5 WANG Wen\|xian, ZHANG Dong (The department of Radiology,Xinqiao Hospital,Third Military Medical University, Chongqing 400037,China) [;Differential Diagnosis of Untypical Imaging Signs of Brain Astrocytoma[J];CHINESE JOURNAL OF MEDICAL IMAGING TECHNOLOGY;2000-09
6 ZHANG Zhen feng, ZHANG Cheng hui, WU Pei hong, et al (Cancer Center, Sun Yat sen University of Medical Sciences, Guangzhou 510060, China);Misdiagnostic Analysis and Strategies of CT and MRI for Intracranial Mass Lesions[J];Chinese Journal of Medical Imaging Technology;2001-10
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